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Terminated Phase 1Phase 2 Interventional Results available

Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma

ClinicalTrials.gov ID: NCT03319537

Public ClinicalTrials.gov record NCT03319537. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 18, 2026, 8:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Pevonedistat as a Single Agent and in Combination With Chemotherapy in Patients With Malignant Mesothelioma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to test any good and bad effects of activity pevonedistat taken alone, and also to test the safety of pevonedistat in combination with standard chemotherapy, pemetrexed/cisplatin.

Study identification

NCT ID
NCT03319537
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1, Phase 2
Enrollment
9 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 5, 2017 (Actual)
Primary completion
Jun 5, 2023 (Actual)
Completion
Jun 5, 2023 (Actual)
Last update posted
May 23, 2024

2017 – 2023

United States locations

U.S. sites
8
U.S. states
2
U.S. cities
8
Facility City State ZIP Site status
Memorial Sloan Kettering at Basking Ridge Basking Ridge New Jersey 07920 —
Memorial Sloan Kettering Monmouth Middletown New Jersey 07748 —
Memorial Sloan Kettering Bergen Montvale New Jersey 07645 —
Memorial Sloan Kettering Commack Commack New York 11725 —
Memorial Sloan Kettering Westchester Harrison New York 10604 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Memorial Sloan Kettering Rockville Centre Rockville Centre New York 11570 —
Memorial Sloan Kettering Nassau Uniondale New York 11553 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03319537, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 23, 2024 · Synced Oct 18, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03319537 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →