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Active, not recruiting Phase 1 Interventional

Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC)

ClinicalTrials.gov ID: NCT03319940

Public ClinicalTrials.gov record NCT03319940. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 4:55 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study Evaluating the Safety, Tolerability and Pharmacokinetics of Tarlatamab in Subjects With Small Cell Lung Cancer (DeLLphi-300)

Study identification

NCT ID
NCT03319940
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Amgen
Industry
Enrollment
269 participants

Conditions and interventions

Interventions

  • Tarlatamab Drug
  • Pembrolizumab Drug
  • CRS Mitigation Strategies Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 25, 2017
Primary completion
Dec 30, 2026
Completion
Dec 30, 2027
Last update posted
Nov 18, 2025

2017 – 2027

United States locations

U.S. sites
15
U.S. states
13
U.S. cities
15
Facility City State ZIP Site status
City of Hope National Medical Center Duarte California 91010
Yale New Haven Hospital New Haven Connecticut 06510
Moffitt Cancer Center Tampa Florida 33612
Winship Cancer Institute Atlanta Georgia 30322
University of Chicago Chicago Illinois 60637
Ochsner Clinic Foundation New Orleans Louisiana 70121
John Hopkins Sidney Kimmel Comprehensive Cancer Center Baltimore Maryland 21287
Henry Ford Health System Detroit Michigan 48202
Washington University St Louis Missouri 63110-1093
Memorial Sloan Kettering Cancer Center New York New York 10021
University Hospitals Cleveland Medical Center Cleveland Ohio 44106
The Ohio State University Wexner Medical Center - Thoracic Oncology Clinic Columbus Ohio 43210
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
University of Pittsburgh Medical Center Cancer Pavillion Pittsburgh Pennsylvania 15232
Sarah Cannon Research Institute Nashville Tennessee 37203

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03319940, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 18, 2025 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03319940 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →