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Completed Phase 1Phase 2 Interventional Results available

Evaluation of TTP399 in Patients With Type 1 Diabetes

ClinicalTrials.gov ID: NCT03335371

Public ClinicalTrials.gov record NCT03335371. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 10, 2026, 8:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Randomized, Double-Blind, Parallel-Group, Multiple-Dose, Adaptive Study Assessing the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of TTP399 in With Adult Patients Type 1 Diabetes Mellitus

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety and efficacy of TTP399 in Type 1 diabetics. This study will be in 2 phases: phase 1 will evaluate the safety of different TTP399 dosage regimens over 1 week of daily dosing. Phase 2 will evaluate the safety and efficacy of a TTP399 dosing regimen over 12 weeks of daily dosing.

Study identification

NCT ID
NCT03335371
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
vTv Therapeutics
Industry
Enrollment
115 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 24, 2017
Primary completion
Dec 19, 2019
Completion
Jan 5, 2020
Last update posted
Jul 2, 2023

2017 – 2020

United States locations

U.S. sites
15
U.S. states
9
U.S. cities
15
Facility City State ZIP Site status
USC Westside Center for Diabetes Beverly Hills California 90211
AMCR Institute Escondido California 92025
University of Colorado Barbara Davis Center Aurora Colorado 80045
Atlanta Diabetes Associate Atlanta Georgia 30318
Rocky Mountain Diabetes Center Idaho Falls Idaho 83404
Iowa Diabetes Research West Des Moines Iowa 50265
Mountain Diabetes and Endocrine Center Asheville North Carolina 28803
UNC Diabetes Care Center Chapel Hill North Carolina 27517
Duke University Diabetes Research Clinic Durham North Carolina 27710
Diabetes & Endocrinology Consultants Morehead City North Carolina 28557
PMG Research of Wilmington Wilmington North Carolina 28401
Wake Forest Winston-Salem North Carolina 27104
Intend Research Norman Oklahoma 73069
Dallas Diabetes Research Center Dallas Texas 75230
University of Washington Medicine Diabetes Institute Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03335371, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 2, 2023 · Synced Sep 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03335371 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →