Study to Evaluate Tezepelumab in Adults & Adolescents With Severe Uncontrolled Asthma
Public ClinicalTrials.gov record NCT03347279. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Randomized, Double-Blind, Placebo Controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults and Adolescents With Severe Uncontrolled Asthma (NAVIGATOR)
Study identification
- NCT ID
- NCT03347279
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 1,061 participants
Conditions and interventions
Conditions
Interventions
- Experimental: Tezepelumab Biological
- Placebo Other
Biological · Other
Eligibility (public fields only)
- Age range
- 12 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 22, 2017
- Primary completion
- Sep 7, 2020
- Completion
- Nov 11, 2020
- Last update posted
- Nov 25, 2021
2017 – 2020
United States locations
- U.S. sites
- 95
- U.S. states
- 29
- U.S. cities
- 82
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Dothan | Alabama | 36303 | — |
| Research Site | Foley | Alabama | 36535 | — |
| Research Site | Gilbert | Arizona | 85234 | — |
| Research Site | Tucson | Arizona | 85724 | — |
| Research Site | Bakersfield | California | 93301 | — |
| Research Site | Encinitas | California | 92024 | — |
| Research Site | Huntington Beach | California | 92647 | — |
| Research Site | Long Beach | California | 90808 | — |
| Research Site | Los Angeles | California | 90025 | — |
| Research Site | Mission Viejo | California | 92691 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Northridge | California | 91324 | — |
| Research Site | Palm Desert | California | 92260 | — |
| Research Site | Rolling Hills Estates | California | 90274 | — |
| Research Site | Walnut Creek | California | 94598 | — |
| Research Site | Westminster | California | 92683 | — |
| Research Site | Denver | Colorado | 80206 | — |
| Research Site | New Haven | Connecticut | 06520 | — |
| Research Site | Celebration | Florida | 34747 | — |
| Research Site | Kissimmee | Florida | 34741 | — |
| Research Site | Kissimmee | Florida | 34744 | — |
| Research Site | Orlando | Florida | 32803 | — |
| Research Site | Orlando | Florida | 32825 | — |
| Research Site | Panama City | Florida | 32405 | — |
| Research Site | Port Charlotte | Florida | 33952 | — |
| Research Site | Sarasota | Florida | 34239 | — |
| Research Site | Sebring | Florida | 33870 | — |
| Research Site | St. Petersburg | Florida | 33704 | — |
| Research Site | St. Petersburg | Florida | 33710 | — |
| Research Site | St. Petersburg | Florida | 33713 | — |
| Research Site | Tampa | Florida | 33607 | — |
| Research Site | Winter Park | Florida | 32789 | — |
| Research Site | Fayetteville | Georgia | 30214 | — |
| Research Site | Gainesville | Georgia | 30501 | — |
| Research Site | Savannah | Georgia | 31406 | — |
| Research Site | Stockbridge | Georgia | 30281 | — |
| Research Site | Boise | Idaho | 83706 | — |
| Research Site | Michigan City | Indiana | 46360 | — |
| Research Site | Fort Mitchell | Kentucky | 41017 | — |
| Research Site | Louisville | Kentucky | 40215 | — |
| Research Site | Lake Charles | Louisiana | 70601 | — |
| Research Site | Zachary | Louisiana | 70791 | — |
| Research Site | White Marsh | Maryland | 21162 | — |
| Research Site | Boston | Massachusetts | 02115 | — |
| Research Site | Fall River | Massachusetts | 02721 | — |
| Research Site | Ann Arbor | Michigan | 48109 | — |
| Research Site | Flint | Michigan | 48504 | — |
| Research Site | Novi | Michigan | 48375 | — |
| Research Site | Port Huron | Michigan | 48060 | — |
| Research Site | Troy | Michigan | 48085 | — |
| Research Site | St Louis | Missouri | 63108 | — |
| Research Site | St Louis | Missouri | 63141 | — |
| Research Site | Lincoln | Nebraska | 68505 | — |
| Research Site | Las Vegas | Nevada | 89106 | — |
| Research Site | Las Vegas | Nevada | 89119 | — |
| Research Site | Northfield | New Jersey | 08225 | — |
| Research Site | Toms River | New Jersey | 08755 | — |
| Research Site | Brooklyn | New York | 11235 | — |
| Research Site | New York | New York | 10016 | — |
| Research Site | New York | New York | 10022 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | New York | New York | 10032 | — |
| Research Site | The Bronx | New York | 10459 | — |
| Research Site | The Bronx | New York | 10465 | — |
| Research Site | Valhalla | New York | 10595 | — |
| Research Site | Charlotte | North Carolina | 28277 | — |
| Research Site | Gastonia | North Carolina | 28054 | — |
| Research Site | Winston-Salem | North Carolina | 27104 | — |
| Research Site | Cincinnati | Ohio | 45229 | — |
| Research Site | Cincinnati | Ohio | 45231 | — |
| Research Site | Mayfield Heights | Ohio | 44124 | — |
| Research Site | Toledo | Ohio | 43608 | — |
| Research Site | Edmond | Oklahoma | 73034 | — |
| Research Site | Oklahoma City | Oklahoma | 73120 | — |
| Research Site | Tulsa | Oklahoma | 74136 | — |
| Research Site | Medford | Oregon | 97504 | — |
| Research Site | Pittsburgh | Pennsylvania | 15243 | — |
| Research Site | Warwick | Rhode Island | 02886 | — |
| Research Site | Anderson | South Carolina | 29621 | — |
| Research Site | Columbia | South Carolina | 29204 | — |
| Research Site | Greenville | South Carolina | 29607 | — |
| Research Site | Allen | Texas | 75013 | — |
| Research Site | Amarillo | Texas | 79106 | — |
| Research Site | Boerne | Texas | 78006 | — |
| Research Site | Dallas | Texas | 75225 | — |
| Research Site | Dallas | Texas | 75230 | — |
| Research Site | Lampasas | Texas | 76550 | — |
| Research Site | McAllen | Texas | 78504 | — |
| Research Site | Plano | Texas | 75093 | — |
| Research Site | San Antonio | Texas | 78251 | — |
| Research Site | Manassas | Virginia | 20110 | — |
| Research Site | Richmond | Virginia | 23220 | — |
| Research Site | Richmond | Virginia | 23235 | — |
| Research Site | Cudahy | Wisconsin | 53110 | — |
| Research Site | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 194 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03347279, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 25, 2021 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03347279 live on ClinicalTrials.gov.