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Completed Phase 3 Interventional Results available

Study to Evaluate Tezepelumab in Adults & Adolescents With Severe Uncontrolled Asthma

ClinicalTrials.gov ID: NCT03347279

Public ClinicalTrials.gov record NCT03347279. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:47 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicentre, Randomized, Double-Blind, Placebo Controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults and Adolescents With Severe Uncontrolled Asthma (NAVIGATOR)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A Multicentre, Randomized, Double-Blind, Placebo Controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults and Adolescents with Severe Uncontrolled Asthma

Study identification

NCT ID
NCT03347279
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
1,061 participants

Conditions and interventions

Conditions

Interventions

Biological · Other

Eligibility (public fields only)

Age range
12 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 23, 2017 (Actual)
Primary completion
Sep 8, 2020 (Actual)
Completion
Nov 12, 2020 (Actual)
Last update posted
Nov 26, 2021

2017 – 2020

United States locations

U.S. sites
95
U.S. states
29
U.S. cities
82
Facility City State ZIP Site status
Research Site Dothan Alabama 36303 —
Research Site Foley Alabama 36535 —
Research Site Gilbert Arizona 85234 —
Research Site Tucson Arizona 85724 —
Research Site Bakersfield California 93301 —
Research Site Encinitas California 92024 —
Research Site Huntington Beach California 92647 —
Research Site Long Beach California 90808 —
Research Site Los Angeles California 90025 —
Research Site Mission Viejo California 92691 —
Research Site Newport Beach California 92663 —
Research Site Northridge California 91324 —
Research Site Palm Desert California 92260 —
Research Site Rolling Hills Estates California 90274 —
Research Site Walnut Creek California 94598 —
Research Site Westminster California 92683 —
Research Site Denver Colorado 80206 —
Research Site New Haven Connecticut 06520 —
Research Site Celebration Florida 34747 —
Research Site Kissimmee Florida 34741 —
Research Site Kissimmee Florida 34744 —
Research Site Orlando Florida 32803 —
Research Site Orlando Florida 32825 —
Research Site Panama City Florida 32405 —
Research Site Port Charlotte Florida 33952 —
Research Site Sarasota Florida 34239 —
Research Site Sebring Florida 33870 —
Research Site St. Petersburg Florida 33704 —
Research Site St. Petersburg Florida 33710 —
Research Site St. Petersburg Florida 33713 —
Research Site Tampa Florida 33607 —
Research Site Winter Park Florida 32789 —
Research Site Fayetteville Georgia 30214 —
Research Site Gainesville Georgia 30501 —
Research Site Savannah Georgia 31406 —
Research Site Stockbridge Georgia 30281 —
Research Site Boise Idaho 83706 —
Research Site Michigan City Indiana 46360 —
Research Site Fort Mitchell Kentucky 41017 —
Research Site Louisville Kentucky 40215 —
Research Site Lake Charles Louisiana 70601 —
Research Site Zachary Louisiana 70791 —
Research Site White Marsh Maryland 21162 —
Research Site Boston Massachusetts 02115 —
Research Site Fall River Massachusetts 02721 —
Research Site Ann Arbor Michigan 48109 —
Research Site Flint Michigan 48504 —
Research Site Novi Michigan 48375 —
Research Site Port Huron Michigan 48060 —
Research Site Troy Michigan 48085 —
Research Site St Louis Missouri 63108 —
Research Site St Louis Missouri 63141 —
Research Site Lincoln Nebraska 68505 —
Research Site Las Vegas Nevada 89106 —
Research Site Las Vegas Nevada 89119 —
Research Site Northfield New Jersey 08225 —
Research Site Toms River New Jersey 08755 —
Research Site Brooklyn New York 11235 —
Research Site New York New York 10016 —
Research Site New York New York 10022 —
Research Site New York New York 10029 —
Research Site New York New York 10032 —
Research Site The Bronx New York 10459 —
Research Site The Bronx New York 10465 —
Research Site Valhalla New York 10595 —
Research Site Charlotte North Carolina 28277 —
Research Site Gastonia North Carolina 28054 —
Research Site Winston-Salem North Carolina 27104 —
Research Site Cincinnati Ohio 45229 —
Research Site Cincinnati Ohio 45231 —
Research Site Mayfield Heights Ohio 44124 —
Research Site Toledo Ohio 43608 —
Research Site Edmond Oklahoma 73034 —
Research Site Oklahoma City Oklahoma 73120 —
Research Site Tulsa Oklahoma 74136 —
Research Site Medford Oregon 97504 —
Research Site Pittsburgh Pennsylvania 15243 —
Research Site Warwick Rhode Island 02886 —
Research Site Anderson South Carolina 29621 —
Research Site Columbia South Carolina 29204 —
Research Site Greenville South Carolina 29607 —
Research Site Allen Texas 75013 —
Research Site Amarillo Texas 79106 —
Research Site Boerne Texas 78006 —
Research Site Dallas Texas 75225 —
Research Site Dallas Texas 75230 —
Research Site Lampasas Texas 76550 —
Research Site McAllen Texas 78504 —
Research Site Plano Texas 75093 —
Research Site San Antonio Texas 78251 —
Research Site Manassas Virginia 20110 —
Research Site Richmond Virginia 23220 —
Research Site Richmond Virginia 23235 —
Research Site Cudahy Wisconsin 53110 —
Research Site Madison Wisconsin 53792 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 194 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03347279, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 26, 2021 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03347279 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →