Study to Evaluate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis
Public ClinicalTrials.gov record NCT03349060. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUP, MULTI-CENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-04965842 MONOTHERAPY IN SUBJECTS AGED 12 YEARS AND OLDER, WITH MODERATE TO SEVERE ATOPIC DERMATITIS
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
B7451012 is a Phase 3 study to evaluate PF-04965842 in patients aged 12 years and older with a minimum body weight of 40 kg who have moderate to severe atopic dermatitis. The efficacy and safety of two dosage strengths of PF-04965842, 100 mg and 200 mg taken orally once daily, will be evaluated relative to placebo over 12 weeks of study participation. Eligible patients will have an option to enter a long-term extension study after completing 12 weeks of treatment.
Study identification
- NCT ID
- NCT03349060
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 387 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 7, 2017 (Actual)
- Primary completion
- Mar 26, 2019 (Actual)
- Completion
- Mar 26, 2019 (Actual)
- Last update posted
- Dec 10, 2019
2017 – 2019
United States locations
- U.S. sites
- 29
- U.S. states
- 15
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Center of Alabama, LLC | Birmingham | Alabama | 35209 | — |
| California Dermatology & Clinical Research Institute | Encinitas | California | 92024 | — |
| Rady Children's Hospital - San Diego/University of California, San Diego | San Diego | California | 92123 | — |
| TCR Medical Corporation | San Diego | California | 92123 | — |
| Clinical Science Institute | Santa Monica | California | 90404 | — |
| Florida Academic Centers Research and Education, LLC | Coral Gables | Florida | 33134 | — |
| Olympian Clinical Research | Largo | Florida | 33770 | — |
| Forward Clinical Trials, Inc. | Tampa | Florida | 33624 | — |
| Meridian Clinical Research, LLC | Savannah | Georgia | 31406 | — |
| NorthShore University HealthSystem Dermatology Clinical Trials Unit | Skokie | Illinois | 60077 | — |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis | Indiana | 46256 | — |
| Dawes Fretzin Dermatology Group, LLC | Indianapolis | Indiana | 46256 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Henry Ford Medical Center, New Center One | Detroit | Michigan | 48202 | — |
| Somerset Skin Centre | Troy | Michigan | 48084 | — |
| MediSearch Clinical Trials | Saint Joseph | Missouri | 64506 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Vital Prospects Clinical Research Institute, P.C. | Tulsa | Oklahoma | 74136 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Medical University of South Carolina Investigational Drug Services | Charleston | South Carolina | 29425 | — |
| MUSC SCTR Research Nexus Clinic and Laboratory | Charleston | South Carolina | 29425 | — |
| Arlington Research Center, Inc. | Arlington | Texas | 76011 | — |
| The University of Texas Health Science Center Houston | Houston | Texas | 77030 | — |
| Texas Dermatology and Laser Specialists | San Antonio | Texas | 78218 | — |
| Virginia Clinical Research, Inc. | Norfolk | Virginia | 23502 | — |
| Pace Dermatology Associates | Lakewood | Washington | 98499 | — |
| MultiCare Allenmore Hospital | Tacoma | Washington | 98405 | — |
| MultiCare Institute for Research and Innovation | Tacoma | Washington | 98405 | — |
| Pace Dermatology Associates | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 59 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03349060, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 10, 2019 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03349060 live on ClinicalTrials.gov.