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Terminated Phase 2 Interventional Results available

A Study of Rapastinel for Rapid Treatment of Depression and Suicidality in Major Depressive Disorder

ClinicalTrials.gov ID: NCT03352453

Public ClinicalTrials.gov record NCT03352453. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 27, 2026, 2:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Multicenter, Efficacy and Safety Study of Rapastinel for Rapid Treatment of Symptoms of Depression and Suicidality in Adult Patients With Major Depressive Disorder

Study identification

NCT ID
NCT03352453
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Naurex, Inc, an affiliate of Allergan plc
Industry
Enrollment
138 participants

Conditions and interventions

Interventions

  • Rapastinel Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 14, 2017
Primary completion
Jun 20, 2019
Completion
Jun 20, 2019
Last update posted
Aug 13, 2020

2017 – 2019

United States locations

U.S. sites
17
U.S. states
13
U.S. cities
17
Facility City State ZIP Site status
The Board of Trustees of the University of Alabama for the University of Alabama at Birmingham Birmingham Alabama 35294-0107
Collaborative NeuroScience Network, LLC Garden Grove California 92845
Behavioral Research Specialists, LLC Glendale California 91206-4282
Asclepes Research Centers Panorama City California 91402
Institute of Living Hartford Connecticut 06106
Innovative Clinical Research, Inc Hialeah Florida 33012
Research Centers of America, LLC Oakland Park Florida 33334
Atlanta Center for Medical Research (ACMR) Atlanta Georgia 30331
Alexian Brothers Center for Psychiatric Research Hoffman Estates Illinois 60169
Lake Charles Clinical Trials Lake Charles Louisiana 70629
CBH Health Gaithersburg Maryland 20877
Altea Research Institute Las Vegas Nevada 89102
Icahn School of Medicine at Mount Sinai New York New York 10029
Cincinnati VA Medical Center Cincinnati Ohio 45220-2288
Pillar Clinical Research, LLC Richardson Texas 75080
Carilion Medical Center, a Virginia Nonprofit Corporation Roanoke Virginia 24014-2419
Department of Veterans Affairs Salem VA Medical Center Salem Virginia 24153

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03352453, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 13, 2020 · Synced Jun 27, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03352453 live on ClinicalTrials.gov.

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