A Study of Rapastinel for Rapid Treatment of Depression and Suicidality in Major Depressive Disorder
Public ClinicalTrials.gov record NCT03352453. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Multicenter, Efficacy and Safety Study of Rapastinel for Rapid Treatment of Symptoms of Depression and Suicidality in Adult Patients With Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study will evaluate the efficacy, safety, and tolerability of 450 milligrams (mg) of Rapastinel, compared to placebo in adult patients with major depressive disorder (MDD) who are at imminent risk of suicide.
Study identification
- NCT ID
- NCT03352453
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 138 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 15, 2017 (Actual)
- Primary completion
- Jun 21, 2019 (Actual)
- Completion
- Jun 21, 2019 (Actual)
- Last update posted
- Aug 14, 2020
2017 – 2019
United States locations
- U.S. sites
- 17
- U.S. states
- 13
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Board of Trustees of the University of Alabama for the University of Alabama at Birmingham | Birmingham | Alabama | 35294-0107 | — |
| Collaborative NeuroScience Network, LLC | Garden Grove | California | 92845 | — |
| Behavioral Research Specialists, LLC | Glendale | California | 91206-4282 | — |
| Asclepes Research Centers | Panorama City | California | 91402 | — |
| Institute of Living | Hartford | Connecticut | 06106 | — |
| Innovative Clinical Research, Inc | Hialeah | Florida | 33012 | — |
| Research Centers of America, LLC | Oakland Park | Florida | 33334 | — |
| Atlanta Center for Medical Research (ACMR) | Atlanta | Georgia | 30331 | — |
| Alexian Brothers Center for Psychiatric Research | Hoffman Estates | Illinois | 60169 | — |
| Lake Charles Clinical Trials | Lake Charles | Louisiana | 70629 | — |
| CBH Health | Gaithersburg | Maryland | 20877 | — |
| Altea Research Institute | Las Vegas | Nevada | 89102 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Cincinnati VA Medical Center | Cincinnati | Ohio | 45220-2288 | — |
| Pillar Clinical Research, LLC | Richardson | Texas | 75080 | — |
| Carilion Medical Center, a Virginia Nonprofit Corporation | Roanoke | Virginia | 24014-2419 | — |
| Department of Veterans Affairs Salem VA Medical Center | Salem | Virginia | 24153 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03352453, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 14, 2020 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03352453 live on ClinicalTrials.gov.