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Completed Phase 2 Interventional Results available

ZIMURA in Combination With LUCENTIS in Patients With Neovascular Age Related Macular Degeneration (NVAMD)

ClinicalTrials.gov ID: NCT03362190

Public ClinicalTrials.gov record NCT03362190. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 10:50 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2A Open-label Trial to Assess the Safety of ZIMURA™ (Anti-C5) Administered in Combination With LUCENTIS® 0.5 mg in Treatment Naive Subjects With Neovascular Age Related Macular Degeneration

Study identification

NCT ID
NCT03362190
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Ophthotech Corporation
Industry
Enrollment
64 participants

Conditions and interventions

Interventions

  • Avacincaptad Pegol Drug
  • Lucentis Drug

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 10, 2017
Primary completion
Oct 17, 2018
Completion
Oct 17, 2018
Last update posted
Jun 9, 2025

2017 – 2018

United States locations

U.S. sites
23
U.S. states
14
U.S. cities
22
Facility City State ZIP Site status
Retinal Research Institute Phoenix Arizona 85053
Retina Centers PC Tucson Arizona 85704
Retina Associates SW, PC Tucson Arizona 85710
Retina-Vitreous Associates Medical Group Beverly Hills California 90211
Retina Consultants of Orange County Fullerton California 92835
Retina Consultants of Southern California Redlands California 92374
Retinal Consultants Medical Group Sacramento California 95841
Orange County Retina Medical Group Santa Ana California 92705
Colorado Retina Associates Golden Colorado 80214
Florida Eye Clinic Altamonte Springs Florida 32701
Florida Eye Associates Melbourne Florida 32901
Illinois Eye Center Peoria Illinois 61615
Vitreo Retinal Consultants & Surgeons Wichita Kansas 67214
Ophthalmic Consultants of Boston Boston Massachusetts 02114
VitreoRetinal Surgery Minneapolis Minnesota 55435
Retina Consultants of Nevada Henderson Nevada 89052
Sierra Eye Associates Reno Nevada 89502
Retina Vitreous Surgeons of CNY, PC Syracuse New York 13224
Retina Northwest PC Portland Oregon 97221
Mid Atlantic Retina Philadelphia Pennsylvania 19107
Charleston Neuroscience Institute Ladson South Carolina 29456
Retina Research Institute of Texas Abilene Texas 79606
Strategic Clinical Research Group Willow Park Texas 76087

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03362190, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 9, 2025 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03362190 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →