Tralokinumab in Combination With Topical Corticosteroids for Moderate to Severe Atopic Dermatitis - ECZTRA 3
Public ClinicalTrials.gov record NCT03363854. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomised, Double-blind, Placebo-controlled, Phase 3 Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Subjects With Moderate to Severe Atopic Dermatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Primary objective: To demonstrate that tralokinumab in combination with topical corticosteroids (TCS) is superior to placebo in combination with TCS in treating moderate-to-severe atopic dermatitis (AD). Secondary objectives: To evaluate the efficacy of tralokinumab in combination with TCS on severity and extent of AD, itch, and health-related quality of life compared with placebo in combination with TCS. To assess the safety of tralokinumab in combination with TCS when used to treat moderate-to-severe AD for 32 weeks.
Study identification
- NCT ID
- NCT03363854
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 380 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 22, 2018 (Actual)
- Primary completion
- Mar 8, 2019 (Actual)
- Completion
- Sep 26, 2019 (Actual)
- Last update posted
- Mar 11, 2025
2018 – 2019
United States locations
- U.S. sites
- 21
- U.S. states
- 14
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama-Birmingham | Birmingham | Alabama | 35233 | — |
| California Dermatology & Clinical Research Institute | Encinitas | California | 92024 | — |
| First OC Dermatology | Fountain Valley | California | 92708 | — |
| Center for Dermatology Clinical Research | Fremont | California | 94538 | — |
| Dermatology Research Associates | Los Angeles | California | 90045 | — |
| Clinical Science Institute | Santa Monica | California | 90404 | — |
| Danbury Clinical Research | Danbury | Connecticut | 06810 | — |
| International Dermatology Research | Miami | Florida | 33144 | — |
| L & C Professional Medical Research | Miami | Florida | 33144 | — |
| Lenus Research & Medical Group | Sweetwater | Florida | 33172 | — |
| Olympian Clinical Research | Tampa | Florida | 33614 | — |
| Medical Dermatology Specialists | Atlanta | Georgia | 30328 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Indiana Clinical Trials Center | Plainfield | Indiana | 46168 | — |
| Study Center | Bangor | Maine | 04401 | — |
| Respiratory Medicine Research | Ypsilanti | Michigan | 48197 | — |
| Mount Sinai West Dermatoogy | New York | New York | 10023 | — |
| Wake Research | Raleigh | North Carolina | 27612 | — |
| Dermatologists of Greater Columbus | Bexley | Ohio | 43209 | — |
| Oregon Dermatology & Research | Portland | Oregon | 97210 | — |
| National Allergy and Asthma Research, LLC | North Charleston | South Carolina | 29420 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03363854, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 11, 2025 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03363854 live on ClinicalTrials.gov.