A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab
Public ClinicalTrials.gov record NCT03368859. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2 Study Comparing Efficacy and Safety of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A study to evaluate the efficacy and tolerability of ABT-165 plus FOLFIRI compared to bevacizumab plus FOLFIRI in participants with previously treated metastatic adenocarcinoma of the colon or rectum.
Study identification
- NCT ID
- NCT03368859
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 70 participants
Conditions and interventions
Conditions
Interventions
- Leucovorin Drug
- Fluorouracil - bolus Drug
- Bevacizumab Drug
- Fluorouracil - infusion Drug
- ABT-165 Drug
- Irinotecan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 20, 2018 (Actual)
- Primary completion
- Dec 18, 2019 (Actual)
- Completion
- Dec 18, 2019 (Actual)
- Last update posted
- Feb 9, 2021
2018 – 2019
United States locations
- U.S. sites
- 46
- U.S. states
- 27
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ironwood Cancer & Res Ctr /ID# 200044 | Chandler | Arizona | 85224-5665 | — |
| Highlands Oncology Group /ID# 169289 | Fayetteville | Arkansas | 72703-4005 | — |
| City of Hope /ID# 200501 | Duarte | California | 91010 | — |
| St. Joseph Heritage Healthcare /ID# 200100 | Fullerton | California | 92835 | — |
| USC Norris Cancer Center /ID# 200410 | Los Angeles | California | 90033 | — |
| Hoag Memorial Hosp Presbyterian /ID# 202661 | Newport Beach | California | 92663 | — |
| Torrance Health Association (DBA)Torrance Memorial Physician Network/Cancer Care /ID# 202488 | Redondo Beach | California | 90277-3036 | — |
| UC Davis Comprehensive Cancer Center - Main /ID# 207227 | Sacramento | California | 95817 | — |
| Pacific Central Coast Health Centers-SLO Oncology and Hematology Health Center /ID# 201215 | San Luis Obispo | California | 93401-7068 | — |
| Central Coast Medical Oncology /ID# 200227 | Santa Maria | California | 93454-5909 | — |
| University of California, Los /ID# 169294 | Santa Monica | California | 90404 | — |
| Kaiser Permanente, Waterpark III Institute for Health Research /ID# 200801 | Aurora | Colorado | 80014 | — |
| Georgetown University Hospital /ID# 202903 | Washington D.C. | District of Columbia | 20007 | — |
| Florida Cancer Specialist - South /ID# 203796 | Fort Myers | Florida | 33901-8108 | — |
| Florida Cancer Specialists-Panhandle /ID# 203787 | Tallahassee | Florida | 32308-5304 | — |
| IACT Health /ID# 169292 | Columbus | Georgia | 31904-8946 | — |
| Ingalls Memorial Hosp /ID# 169892 | Harvey | Illinois | 60426 | — |
| Illinois Cancer Care, PC /ID# 202189 | Peoria | Illinois | 61615 | — |
| Fort Wayne Medical Oncology /ID# 201616 | Fort Wayne | Indiana | 46804 | — |
| Cancer Center of Kansas /ID# 200627 | Wichita | Kansas | 67214 | — |
| Norton Cancer Institute /ID# 200674 | Louisville | Kentucky | 40207 | — |
| Ochsner Clinic Foundation-New Orleans /ID# 169291 | New Orleans | Louisiana | 70121 | — |
| Whiteside Institute for Clinic /ID# 200802 | Duluth | Minnesota | 55805 | — |
| Mmcorc /Id# 202099 | Saint Louis Park | Minnesota | 55416 | — |
| Washington University School /ID# 200621 | St Louis | Missouri | 63108 | — |
| University of Nebraska /ID# 203195 | Omaha | Nebraska | 68198 | — |
| The Valley Hospital /ID# 169999 | Paramus | New Jersey | 07652 | — |
| Duke University Medical Center /ID# 169657 | Durham | North Carolina | 27710-3000 | — |
| Fairview Hospital - Moll Pavilion /ID# 205910 | Cleveland | Ohio | 44111-5605 | — |
| Cleveland Clinic Main Campus /ID# 200325 | Cleveland | Ohio | 44195 | — |
| Hillcrest Hospital /ID# 205911 | Mayfield Heights | Ohio | 44124 | — |
| INTEGRIS Cancer Institute of OK/INTEGRIS Southwest Medical Center /ID# 200831 | Oklahoma City | Oklahoma | 73109-3411 | — |
| INTEGRIS Cancer Institute /ID# 200832 | Oklahoma City | Oklahoma | 73142 | — |
| Oregon Health and Science University /ID# 170807 | Portland | Oregon | 97239 | — |
| Thomas Jefferson University /ID# 200833 | Philadelphia | Pennsylvania | 19107-4414 | — |
| UPMC Hillman Cancer Ctr /ID# 200672 | Pittsburgh | Pennsylvania | 15232 | — |
| Greenville Hospital System /ID# 203021 | Greenville | South Carolina | 29605 | — |
| Tennessee Oncology-Nashville Centennial /ID# 203424 | Nashville | Tennessee | 37203-1632 | — |
| Tennessee Oncology, PLLC /ID# 203581 | Nashville | Tennessee | 37203 | — |
| Ut Southwestern Medical Center /Parkland Health and Hospital System /Id# 210112 | Dallas | Texas | 75235-7709 | — |
| UTSW-Dallas /ID# 204031 | Dallas | Texas | 75390 | — |
| Millennium Oncology /ID# 204925 | Houston | Texas | 77090-1243 | — |
| Virginia Cancer Specialists /ID# 169293 | Fairfax | Virginia | 22031 | — |
| Kadlec Clinic Hematology and O /ID# 170811 | Kennewick | Washington | 99336 | — |
| Medical Oncology Associates /ID# 169290 | Spokane | Washington | 99208 | — |
| Univ of Wisconsin Hosp/Clinics /ID# 200424 | Madison | Wisconsin | 53792-0001 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03368859, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 9, 2021 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03368859 live on ClinicalTrials.gov.