A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder
Public ClinicalTrials.gov record NCT03375203. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Multicenter, Double-Blind, Randomized, Parallel-Group, Active- and Placebo-Controlled Polysomnography Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42847922 in Subjects With Insomnia Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this 2 month phase 2b study is to investigate the dose response of 3 doses of JNJ-42847922 (Seltorexant) (5,10 and 20 mg) compared to placebo and zolpidem on sleep onset and maintenance and to further document safety and tolerability of JNJ-42847922 (Seltorexant) upon multiple (14 days) dose administration in participants with insomnia disorder.
Study identification
- NCT ID
- NCT03375203
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 365 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- JNJ-42847922, 5 mg Drug
- JNJ-42847922, 10 mg Drug
- JNJ-42847922, 20 mg Drug
- Zolpidem Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 23, 2017 (Actual)
- Primary completion
- Apr 3, 2019 (Actual)
- Completion
- Apr 3, 2019 (Actual)
- Last update posted
- Apr 29, 2025
2017 – 2019
United States locations
- U.S. sites
- 24
- U.S. states
- 12
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Preferred Research Partners | Little Rock | Arkansas | 72211 | — |
| Woodland Research Northwest | Rogers | Arkansas | 72758 | — |
| California Research Trials DBA Orange Country Research Institute | Anaheim | California | 92801 | — |
| Excell Research Inc | Oceanside | California | 92056 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Empire Clinical Research, LLC | Upland | California | 91786 | — |
| St. Francis Medical Institute | Clearwater | Florida | 33765-2103 | — |
| Avail Clinical Research, LLC | DeLand | Florida | 32720 | — |
| Sarkis Clinical Trials | Lake City | Florida | 32025 | — |
| Innovative Clinical Research Inc | Lauderhill | Florida | 33319 | — |
| Suncoast Research Group | Miami | Florida | 33135 | — |
| Renstar Medical Research | Ocala | Florida | 34471 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| NeuroTrials Research, Inc. | Atlanta | Georgia | 30342 | — |
| Chicago Research Center | Chicago | Illinois | 60634 | — |
| Centennial Medical Group | Elkridge | Maryland | 21075 | — |
| Clinical Research Center of Nevada | Las Vegas | Nevada | 89104 | — |
| Gastonia Medical Specialty Clinic | Gastonia | North Carolina | 28054 | — |
| Clinical Research of Lake Norman | Mooresville | North Carolina | 28117 | — |
| CTI Clinical Trial and Consulting Services | Cincinnati | Ohio | 45242 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Clinical Research of Charleston | Mt. Pleasant | South Carolina | 29464 | — |
| FutureSearch Trials of Neurology, LP | Austin | Texas | 78731 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03375203, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 29, 2025 · Synced Nov 8, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03375203 live on ClinicalTrials.gov.