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Completed No phase listed Observational

Spreading Depolarizations in Traumatic Brain Injury

ClinicalTrials.gov ID: NCT03379220

Public ClinicalTrials.gov record NCT03379220. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 9:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Development and Validation of Spreading Depolarization Monitoring for TBI Management

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This research aims to extend the application of spreading depolarization monitoring to non-surgical TBI patients, using intraparenchymal electrode arrays and scalp electroencephalography to detect depolarizations and develop less invasive monitoring methods.

Study identification

NCT ID
NCT03379220
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Lead sponsor
University of Cincinnati
Other
Enrollment
147 participants

Conditions and interventions

Interventions

Not listed

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 28, 2017 (Actual)
Primary completion
Jun 15, 2021 (Actual)
Completion
Jun 15, 2022 (Actual)
Last update posted
Dec 22, 2025

2017 – 2022

United States locations

U.S. sites
7
U.S. states
6
U.S. cities
7
Facility City State ZIP Site status
University of California San Francisco San Francisco California 94110 —
University of Miami Miami Florida 33136 —
Massachusetts General Hospital Boston Massachusetts 02114 —
University of Cincinnati Cincinnati Ohio 45267 —
University of Pennsylvania Philadelphia Pennsylvania 19104 —
University of Pittsburgh Pittsburgh Pennsylvania 15213 —
Baylor College of Medicine Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03379220, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 22, 2025 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03379220 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →