A Study to Explore the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of JNJ-53718678 at Two Dose Levels in Non-Hospitalized Adult Participants Infected With Respiratory Syncytial Virus
Public ClinicalTrials.gov record NCT03379675. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Pilot Phase 2a, Randomized, Double-blind, Placebo-controlled Study to Explore the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of JNJ-53718678 at Two Dose Levels in Non-Hospitalized Adult Subjects Infected With Respiratory Syncytial Virus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to explore the antiviral effect of JNJ-53718678 at 2 dose levels (80 milligrams \[mg\] and 500 mg) once daily for 7 days in adults with Respiratory Syncytial Virus (RSV) infection, as measured by RSV viral load in nasal secretions by quantitative reverse transcription polymerase chain reaction (qRT-PCR) assay.
Study identification
- NCT ID
- NCT03379675
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 72 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 5, 2018
- Primary completion
- Nov 26, 2019
- Completion
- Dec 25, 2019
- Last update posted
- Feb 3, 2025
2018 – 2019
United States locations
- U.S. sites
- 13
- U.S. states
- 9
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Core Healthcare Group | Cerritos | California | 90703 | — |
| eStudySite | Chula Vista | California | 919111 | — |
| SC Clinical Research Inc | Garden Grove | California | 92844 | — |
| Lake Internal Medicine Associates | Eustis | Florida | 32726 | — |
| Florida Research Center Inc. | Miami | Florida | 33174 | — |
| Family Medicine | Nampa | Idaho | 83686 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| AllinaHealth - Abbott Northwestern Hospital (13520) | Minneapolis | Minnesota | 55407 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Onsite Clinical Solutions | Charlotte | North Carolina | 28277 | — |
| Unity Clinical Research | Lindsay | Oklahoma | 73052 | — |
| Spectrum Medical Research | Gaffney | South Carolina | 29341 | — |
| Fusion Clinical Research of Spartanburg | Spartanburg | South Carolina | 29301 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 111 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03379675, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 3, 2025 · Synced Sep 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03379675 live on ClinicalTrials.gov.