Study of Pegilodecakin (LY3500518) With Pembrolizumab Compared to Pembrolizumab Alone First-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer
Public ClinicalTrials.gov record NCT03382899. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase 2 Trial of AM0010 in Combination With Pembrolizumab vs. Pembrolizumab Alone as First-Line (1L) Therapy in Patients With Stage IV / Metastatic Wild Type (WT) Non-Small Cell Lung Cancer and Tumors With High Expression of PD-L1 (> 50%)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To compare the efficacy of pegilodecakin in combination with pembrolizumab versus pembrolizumab alone in participants with metastatic non-small cell lung cancer as measured by objective response rate.
Study identification
- NCT ID
- NCT03382899
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 101 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 19, 2018 (Actual)
- Primary completion
- Dec 6, 2019 (Actual)
- Completion
- Mar 5, 2020 (Actual)
- Last update posted
- Jan 20, 2021
2018 – 2020
United States locations
- U.S. sites
- 74
- U.S. states
- 32
- U.S. cities
- 69
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CCI - Clearview Cancer Institute | Huntsville | Alabama | 35805 | — |
| Arizona Oncology Associates, P.C. | Tempe | Arizona | 85284 | — |
| Beverly Hills Cancer Center | Beverly Hills | California | 90211 | — |
| St. Joseph Heritage Medical Group | Fullerton | California | 92835 | — |
| Glendale Adventist Medical Center | Los Angeles | California | 90017 | — |
| Redlands Community Hospital | Redlands | California | 92373 | — |
| Redwood Regional Oncology Center | Santa Rosa | California | 95403 | — |
| The Oncology Institute of Hope and Innovation | Whittier | California | 90602 | — |
| Memorial Hospital | Colorado Springs | Colorado | 80909 | — |
| Kaiser Permanente Oncology Clinic | Denver | Colorado | 80205 | — |
| Rocky Mountain Cancer Center | Lone Tree | Colorado | 80124 | — |
| Veterans Affairs Connecticut Healthcare System | West Haven | Connecticut | 06516-2770 | — |
| Medical Oncology Hematolgy Consultants, PA | Newark | Delaware | 19713 | — |
| Lynn Cancer Institute Ctr for Hem-Onc | Boca Raton | Florida | 33486 | — |
| Memorial Cancer Institute | Pembroke Pines | Florida | 33028 | — |
| SCRI- Florida Cancer Specialists | Tallahassee | Florida | 32308 | — |
| Tallahassee Memorial Cancer Center | Tallahassee | Florida | 32308 | — |
| Florida Cancer Specialists East | West Palm Beach | Florida | 33401 | — |
| Northeast Georgia Cancer Care, LLC | Athens | Georgia | 30607 | — |
| Pacific Diabetes & Endocrine Center | Honolulu | Hawaii | 96813 | — |
| AMITA Health Cancer Institute & Outpatient Center | Hinsdale | Illinois | 60521 | — |
| Orchard Healthcare Research Inc | Skokie | Illinois | 60077 | — |
| Goshen Health System | Goshen | Indiana | 46526 | — |
| University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| Covenant Clinic | Waterloo | Iowa | 50702 | — |
| Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| Baptist Health Medical Group | Lexington | Kentucky | 40503 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | — |
| MedStar Research Institute | Baltimore | Maryland | 21237 | — |
| Maryland Oncology Hematology, P.A. | Columbia | Maryland | 21044 | — |
| Frederick Memorial Hospital | Frederick | Maryland | 21701 | — |
| St. Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | — |
| Henry Ford Hospital Detroit | Detroit | Michigan | 48202 | — |
| Sparrow Health System | Lansing | Michigan | 48912 | — |
| Minnesota Oncology/Hematology PA | Minneapolis | Minnesota | 55404 | — |
| University of Minnesota Hospital | Minneapolis | Minnesota | 55455 | — |
| Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | — |
| St John's Mercy Medical Center | St Louis | Missouri | 63141 | — |
| Nebraska Hematology-Oncology | Lincoln | Nebraska | 68506 | — |
| Morristown Medical Center | Morristown | New Jersey | 07962 | — |
| The Valley Hospital - Luckow Pavilion | Westwood | New Jersey | 07675 | — |
| Clinical Research Alliance, Inc. | Lake Success | New York | 11042 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| DJL Clinical Research, PLLC | Charlotte | North Carolina | 28207 | — |
| Southeastern Medical Oncology Center | Jacksonville | North Carolina | 28546 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| Christ Hospital | Cincinnati | Ohio | 45219 | — |
| University of Toledo Medical Center | Toledo | Ohio | 43614-2598 | — |
| The Toledo Clinic | Toledo | Ohio | 43623 | — |
| Oncology Associates of Oregon | Eugene | Oregon | 97401 | — |
| Charleston Hematology Oncology Associates | Charleston | South Carolina | 29414 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Chattanooga Oncology Hematology Associates | Chattanooga | Tennessee | 37404 | — |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916 | — |
| Sarah Cannon Research Institute SCRI | Nashville | Tennessee | 37203 | — |
| Texas Cancer Center (Abilene) | Abilene | Texas | 79606 | — |
| Mamie McFaddin Ward Cancer Center | Beaumont | Texas | 77702 | — |
| Texas Oncology - Dallas Presbyterian Hospital | Dallas | Texas | 75231 | — |
| Texas Oncology-Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Texas Oncology-Memorial City | Houston | Texas | 77024 | — |
| Millennium Oncology | Houston | Texas | 77090 | — |
| Joe Arrington Cancer Center | Lubbock | Texas | 79410 | — |
| Texas Oncology - Midland Allison Cancer Center | Midland | Texas | 79701 | — |
| Texas Oncology-Sherman | Sherman | Texas | 75090-0504 | — |
| US Oncology | The Woodlands | Texas | 77380 | — |
| Texas Oncology - Tyler | Tyler | Texas | 75702 | — |
| Texas Oncology-Deke Slayton Cancer Center | Webster | Texas | 77598-4219 | — |
| Texas Oncology-Wichital Falls Texoma Cancer Center | Wichita Falls | Texas | 76310 | — |
| Fairfax Northern Virginia Hematology Oncology, PC | Fairfax | Virginia | 22031 | — |
| Oncology and Hematology Associates of Southwest Virginia Inc | Roanoke | Virginia | 24014 | — |
| Shenandoah Oncology, P.C. | Winchester | Virginia | 22601 | — |
| MultiCare Regional Cancer Center - Auburn | Tacoma | Washington | 98002 | — |
| The Richland Hospital | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03382899, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 20, 2021 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03382899 live on ClinicalTrials.gov.