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Terminated Phase 1Phase 2 Interventional

Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects

ClinicalTrials.gov ID: NCT03382977

Public ClinicalTrials.gov record NCT03382977. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:24 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Three-part, Phase I/II Dose-Escalation Study to Define the Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 With Subsequent Extension of Optimal Dose in Recurrent GBM Subjects

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the safety and tolerability of VBI-1901 in subjects with recurrent malignant gliomas (glioblastoma, or GBM).

Study identification

NCT ID
NCT03382977
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
VBI Vaccines Inc.
Industry
Enrollment
70 participants

Conditions and interventions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 5, 2017
Primary completion
Jul 29, 2025
Completion
Aug 29, 2025
Last update posted
May 7, 2026

2017 – 2025

United States locations

U.S. sites
12
U.S. states
8
U.S. cities
11
Facility City State ZIP Site status
University of California, Irvine Irvine California 92868
University of California, San Diego La Jolla California 92093
University of California, Los Angeles Neuro-Oncology Program Los Angeles California 90095
Stanford Stanford California 94305
Miami Cancer Institute Miami Florida 33176
Massachusetts General Hospital Boston Massachusetts 02114
Dana-Farber Cancer Institute Boston Massachusetts 02215
The Valley Hospital - Neurosurgeons of New Jersey Ridgewood New Jersey 07450
The Neurological Institute of New York Columbia University Medical Center New York New York 10032
Vanderbilt University Medical Center Nashville Tennessee 37232
MD Anderson Cancer Center Houston Texas 77030
Providence - Swedish Medical Center Seattle Washington 98122

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03382977, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 7, 2026 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03382977 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →