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Terminated Phase 3 Interventional Results available

Efficacy and Bone Safety of Sotagliflozin 400 and 200 mg Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control

ClinicalTrials.gov ID: NCT03386344

Public ClinicalTrials.gov record NCT03386344. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 26-week Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Phase 3 Study With a 78-week Extension Period to Evaluate the Efficacy and Bone Safety of Sotagliflozin in Patients 55 Years or Older With Type 2 Diabetes Mellitus and Inadequate Glycemic Control

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective is to demonstrate the superiority of Sotagliflozin 400 milligrams (mg) versus placebo with respect to hemoglobin A1c (Hb1Ac) reduction in participants with type 2 diabetes (T2D) who have inadequate glycemic control on diet and exercise only or with a stable antidiabetes regimen.

Study identification

NCT ID
NCT03386344
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Lexicon Pharmaceuticals
Industry
Enrollment
376 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
55 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 18, 2018
Primary completion
May 21, 2019
Completion
May 29, 2020
Last update posted
Jun 24, 2021

2018 – 2020

United States locations

U.S. sites
14
U.S. states
9
U.S. cities
14
Facility City State ZIP Site status
Investigational Site Number 8409009 Escondido California 92025
Investigational Site Number 8409010 Greenbrae California 94904
Investigational Site Number 8409005 Walnut Creek California 94598
Investigational Site Number 8409012 Columbus Georgia 31904
Investigational Site Number 8409011 Evansville Indiana 47714-8011
Investigational Site Number 8409014 Wichita Kansas 67205-1138
Investigational Site Number 8409015 Albuquerque New Mexico 87106
Investigational Site Number 8409002 Chapel Hill North Carolina 27517
Investigational Site Number 8409001 Wilmington North Carolina 28401-6638
Investigational Site Number 8409008 Dayton Ohio 45419-4336
Investigational Site Number 8409004 Chattanooga Tennessee 37404
Investigational Site Number 8409013 Austin Texas 78749
Investigational Site Number 8409003 Dallas Texas 75230
Investigational Site Number 8409007 Katy Texas 77450

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03386344, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 24, 2021 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03386344 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →