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Completed Phase 2Phase 3 Interventional Results available

Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial

ClinicalTrials.gov ID: NCT03389555

Public ClinicalTrials.gov record NCT03389555. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:09 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Ascorbic Ccid, Hydrocortisone, and Thiamine in Sepsis and Septic Shock - A Randomized, Double-Blind, Placebo-Controlled Trial

Study identification

NCT ID
NCT03389555
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Enrollment
205 participants

Conditions and interventions

Interventions

  • vitamin C, vitamin B1, hydrocortisone Drug
  • Normal saline Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 8, 2018
Primary completion
Nov 25, 2019
Completion
Feb 27, 2020
Last update posted
Feb 15, 2021

2018 – 2020

United States locations

U.S. sites
13
U.S. states
6
U.S. cities
9
Facility City State ZIP Site status
Mayo Clinic - Arizona Phoenix Arizona 85054
Brigham and Women's Hospital Boston Massachusetts 02115
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
Mount Auburn Hospital Cambridge Massachusetts 02138
Detroit Receiving Hospital Detroit Michigan 48201
Harper University Hospital Detroit Michigan 48201
Henry Ford Hospital Detroit Michigan 48202
Sinai Grace Hospital Detroit Michigan 48235
Beaumont Hospital Royal Oak Michigan 48073
North Shore University Hospital Manhasset New York 11030
Long Island Jewish Hospital New York New York 11040
University Of Pittsburgh Medical Center Pittsburgh Pennsylvania 15213
The University of Texas Health Science Center Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03389555, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 15, 2021 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03389555 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →