ClinicalTrials.gov record
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
ClinicalTrials.gov ID: NCT03393520
Public ClinicalTrials.gov record NCT03393520. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-design Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will be conducted to evaluate the efficacy, safety, and tolerability of AVP-786 compared to placebo, for the treatment of agitation in participants with dementia of the Alzheimer's type.
Study identification
- NCT ID
- NCT03393520
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 601 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 12, 2017
- Primary completion
- Nov 16, 2023
- Completion
- Dec 13, 2023
- Last update posted
- Nov 19, 2024
2017 – 2023
United States locations
- U.S. sites
- 93
- U.S. states
- 21
- U.S. cities
- 71
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MD First Research #767 | Chandler | Arizona | 85286 | — |
| Liv Generations of Agritopia / CCT #573 | Gilbert | Arizona | 85296 | — |
| Liv Generations of Ahwatukee / CCT #784 | Phoenix | Arizona | 85048 | — |
| Perseverance Research Center | Scottsdale | Arizona | 85254 | — |
| Medical Advancement Center of Arizona #820 | Tempe | Arizona | 85283 | — |
| Clinical Trials Inc. | Little Rock | Arkansas | 72205 | — |
| Advanced Research Center, Inc #835 | Anaheim | California | 92805 | — |
| ATP Clinical Research, Inc #763 | Costa Mesa | California | 92626 | — |
| Paradigm Clinical Research Centers, Inc. | La Mesa | California | 91942 | — |
| Sunwise Clinical Research #831 | Lafayette | California | 94549 | — |
| Torrance Clinical Research Institute, Inc. #826 | Lomita | California | 90717 | — |
| Rohun Medical Corporation Site #770 | Long Beach | California | 90805 | — |
| Alliance for Wellness, Inc dba Alliance for Research #789 | Long Beach | California | 90807 | — |
| Havana Research Institute | Pasadena | California | 91105 | — |
| Neurology of Central Florida Rsch Ctr # 803 | Altamonte Springs | Florida | 32714 | — |
| Negron Research Services / Humanity Clinical Research #766 | Aventura | Florida | 33180 | — |
| SFM Clinical Research, LLC #563 | Boca Raton | Florida | 33487 | — |
| Helix Biomedics LLC | Boynton Beach | Florida | 33436 | — |
| Bradenton Research Center #834 | Bradenton | Florida | 34205 | — |
| Clinical Research of Brandon #838 | Brandon | Florida | 33511 | — |
| ASCLEPES Research Center #806 | Brooksville | Florida | 34613 | — |
| Beautiful Minds Clinical Research Center #808 | Cutler Bay | Florida | 33157 | — |
| Science Connections, LLC #814 | Doral | Florida | 33178 | — |
| ConSalud Medical Research #773 | Hialeah | Florida | 33012 | — |
| Direct Helpers Research Center # 801 | Hialeah | Florida | 33012 | — |
| New Med Research Inc #812 | Hollywood | Florida | 33020 | — |
| Alphab Global Research #793 | Jupiter | Florida | 33458 | — |
| Alzheimer's Research and Treatment Center | Lake Worth | Florida | 33449 | — |
| Meridien Research - Lakeland Site Site #558 | Lakeland | Florida | 33805 | — |
| Zynak Clinical Services | Lauderdale Lakes | Florida | 33313 | — |
| Adaptive Clinical Research, Inc. Site# 815 | Lauderhill | Florida | 33319 | — |
| Innovative Clinical Research, Inc Site #819 | Lauderhill | Florida | 33319 | — |
| Homestead Associates in Research #797 | Miami | Florida | 33032 | — |
| Premier Clinical Research Institute, Inc. #817 | Miami | Florida | 33122 | — |
| Central Miami Medical Institute # 798 | Miami | Florida | 33125 | — |
| Project4Research #774 | Miami | Florida | 33125 | — |
| City Medical Group RC | Miami | Florida | 33126 | — |
| Finlay Medical Research Corp #552 | Miami | Florida | 33126 | — |
| First Class Medical Services #807 | Miami | Florida | 33126 | — |
| Miami Jewish Health Systems, Inc. #786 | Miami | Florida | 33137 | — |
| New Horizon Research Center Site #795 | Miami | Florida | 33165 | — |
| Reliant Medical Research, LLC #811 | Miami | Florida | 33165 | — |
| Clinical Research Associates of South Florida | Miami | Florida | 33172 | — |
| P&S Research, LLC #805 | Miami | Florida | 33175 | — |
| Pharmax Research of South Florida | Miami | Florida | 33175 | — |
| Research Institute of West Kendall | Miami | Florida | 33186 | — |
| Crystal Biomedical Research, LLC | Miami Lakes | Florida | 33014 | — |
| Agility Medical Research, Inc Site #816 | Miami Lakes | Florida | 33016 | — |
| Bayside Clinical Research | New Port Richey | Florida | 34655 | — |
| Combined Research Orlando #799 | Orlando | Florida | 32807 | — |
| Innovation Medical Research Center #802 | Palmetto | Florida | 33157 | — |
| Quantum Laboratories Site #768 | Pompano Beach | Florida | 33064 | — |
| Neurostudies Inc. Site# 796 | Port Charlotte | Florida | 33952 | — |
| VICIS Clinical Research Inc. #777 | Tampa | Florida | 33615 | — |
| Academic Alliance in Dermatology | Tampa | Florida | 33617 | — |
| JSV Clinical Research Study, Inc. #829 | Tampa | Florida | 33634 | — |
| NeuroStudies. Net, LLC | Decatur | Georgia | 30033 | — |
| Hawaii Pacific Neuroscience #833 | Honolulu | Hawaii | 96817 | — |
| DelRicht Research #776 | Covington | Louisiana | 70443 | — |
| Alzheimer Disease Center #804 | Braintree | Massachusetts | 02184 | — |
| Neurobehavioral Medicine Group #828 | Bloomfield | Michigan | 48302 | — |
| Onyx Clinical Research, LLC | Caro | Michigan | 48723 | — |
| Oakland Medical Research #762 | Troy | Michigan | 48085 | — |
| Precise Research Centers Site #765 | Flowood | Mississippi | 39232 | — |
| Galen Research Site #550 | Chesterfield | Missouri | 63005 | — |
| Psychiatric Care and Research Center #827 | O'Fallon | Missouri | 63368 | — |
| Bio Behavioral Health | Toms River | New Jersey | 08755 | — |
| Mid Hudson Medical Research, PLLC #836 | New Windsor | New York | 12553 | — |
| Nathan S. Kline Institute for Psychiatric Research | Orangeburg | New York | 10962 | — |
| Five Towns Neurology PC/Village Site #764 | Woodmere | New York | 11598 | — |
| The Neurological Institute #843 | Charlotte | North Carolina | 28204 | — |
| New Hope Clinical Research | Charlotte | North Carolina | 28211 | — |
| Insight Clinical Trials LLC #570 | Beachwood | Ohio | 44122 | — |
| Valley Medical Research Site#788 | Centerville | Ohio | 45459 | — |
| Osumc #837 | Columbus | Ohio | 43221 | — |
| NorthStar Medical Research #778 | Middleburg Heights | Ohio | 44130 | — |
| Onyx Clinical Research, LLC | Youngstown | Ohio | 44505 | — |
| Newton Clinical Research | Oklahoma City | Oklahoma | 73102 | — |
| Orenda Research & Consulting LLC #840 | Oklahoma City | Oklahoma | 73170 | — |
| Keystone Clinical Studies, LLC | Norristown | Pennsylvania | 19403 | — |
| Trinity Universal Research Associates Site #821 | Carrollton | Texas | 75007 | — |
| Texas Neurology #832 | Dallas | Texas | 75206 | — |
| InSite Clinical Research | DeSoto | Texas | 75115 | — |
| Bio Pharma Informatic LLC Site #822 | Houston | Texas | 77043 | — |
| Bio Pharma Informatic Inc Site #769 | Houston | Texas | 77084 | — |
| Katy Neurology #823 | Katy | Texas | 77450 | — |
| Northpointe Psychiatry #761 | Lewisville | Texas | 75057 | — |
| Wellness Clinical Research #824 | McKinney | Texas | 75071 | — |
| PRX Research Site #825 | Mesquite | Texas | 75149 | — |
| Wasatch Clinical Research, LLC Site #771 | Salt Lake City | Utah | 84107 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| Core Clinical Research # 772 | Everett | Washington | 98201 | — |
| IPC Research | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 118 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03393520, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 19, 2024 · Synced Sep 1, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03393520 live on ClinicalTrials.gov.