A Study of Rilzabrutinib in Adult Patients With Immune Thrombocytopenia (ITP)
Public ClinicalTrials.gov record NCT03395210. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Adaptive, Open-Label, Dose-Finding, Phase 1/2 Study Investigating the Safety, Pharmacokinetics, and Clinical Activity of PRN1008, an Oral BTK Inhibitor, in Patients With Relapsed Immune Thrombocytopenia
Study identification
- NCT ID
- NCT03395210
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Principia Biopharma, a Sanofi Company
- Industry
- Enrollment
- 86 participants
Conditions and interventions
Conditions
Interventions
- Rilzabrutinib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 21, 2018
- Primary completion
- Jan 30, 2023
- Completion
- Dec 10, 2025
- Last update posted
- Feb 22, 2026
2018 – 2025
United States locations
- U.S. sites
- 8
- U.S. states
- 7
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Bleeding and Clotting Disorders Institute- Site Number : 1087 | Peoria | Illinois | 61614-2868 | — |
| RCCA MC LLC- Site Number : 1091 | Bethesda | Maryland | 20817-1915 | — |
| Massachusetts General Hospital Cancer Center- Site Number : 1092 | Boston | Massachusetts | 02114-2603 | — |
| Beth Israel Deaconess Medical Center- Site Number : 1099 | Boston | Massachusetts | 02215 | — |
| Mid Michigan Medical Center- Site Number : 1086 | Midland | Michigan | 48670 | — |
| New York Presbyterian Hospital/Weill Cornell Medical Center- Site Number : 1097 | New York | New York | 10021 | — |
| Pitt County Memorial Hospital- Site Number : 1095 | Greenville | North Carolina | 27834 | — |
| Seattle Cancer Care Alliance Site Number : 1098 | Seattle | Washington | 98109-4405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03395210, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 22, 2026 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03395210 live on ClinicalTrials.gov.