A Study of VB-111 With Paclitaxel vs Paclitaxel for Treatment of Recurrent Platinum-Resistant Ovarian Cancer (OVAL)
Public ClinicalTrials.gov record NCT03398655. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Controlled, Double-Arm, Double-Blind, Multi-Center Study of Ofranergene Obadenovec (VB-111) Combined With Paclitaxel vs. Paclitaxel Combined With Placebo for the Treatment of Recurrent Platinum-Resistant Ovarian Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this phase 3, randomized, multicenter study is to compare VB-111 and paclitaxel to placebo and paclitaxel in adult patients with Recurrent Platinum-Resistant Ovarian Cancer.
Study identification
- NCT ID
- NCT03398655
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 408 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 19, 2017 (Actual)
- Primary completion
- Jul 19, 2022 (Actual)
- Completion
- Jul 19, 2022 (Actual)
- Last update posted
- Jan 10, 2023
2017 – 2022
United States locations
- U.S. sites
- 64
- U.S. states
- 30
- U.S. cities
- 59
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB Division of GYN Oncology | Birmingham | Alabama | 35344 | — |
| Western Regional Medical Center | Goodyear | Arizona | 85338 | — |
| Arizona Oncology Associates, PC - HAL - USO | Phoenix | Arizona | 85016 | — |
| Arizona Oncology Associates, PC - HAL - USO | Tempe | Arizona | 85284 | — |
| University of Arizona Cancer Center | Tucson | Arizona | 85719 | — |
| UCLA-JCCC-Women's Health Clinical Research Unit | Los Angeles | California | 90095 | — |
| The Center for Cancer Prevention and Treatment at St. Joseph Hospital of Orange | Orange | California | 92868 | — |
| University of California, Irvine Medical Center/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| University of California - San Francisco | San Francisco | California | 94158 | — |
| Sansum Clinic - USO | Santa Barbara | California | 93105 | — |
| Olive View UCLA Medical Center | Sylmar | California | 91342 | — |
| Hartford HealthCare Cancer Institute at the Hospital of Central Ct | Hartford | Connecticut | 06053 | — |
| Hartford Healthcare | Hartford | Connecticut | 06106 | — |
| UF Health | Gainesville | Florida | 32610 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Midwestern Regional Medical Center, Inc | Zion | Illinois | 60099 | — |
| Parkview Cancer Institute | Fort Wayne | Indiana | 46845 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46131 | — |
| St. Vincent Gynecologic Oncology | Indianapolis | Indiana | 46260 | — |
| University of Kansas Cancer Center | Westwood | Kansas | 66205 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Holy Cross Hospital | Silver Spring | Maryland | 20902 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 20114 | — |
| University of Michigan | Ann Arbor | Michigan | 04801 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Henry Ford Health Hospital | Detroit | Michigan | 48202 | — |
| Dartmouth- Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Atlantic Health System/Morristown Medical Center | Morristown | New Jersey | 07928 | — |
| Rutgers New Jersey Medical School | Newark | New Jersey | 07103 | — |
| New Mexico Cancer Care Alliance | Albuquerque | New Mexico | 87106 | — |
| Women's Cancer Care Associates, LLC | Albany | New York | 12208 | — |
| Westchester Medical Center | Hawthorne | New York | 10532 | — |
| Northwell Health Cancer Institute | Lake Success | New York | 11042 | — |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | — |
| Health Quest Medical Practice, Division of Gynecology/Oncology Gyno Dyson Cancer Center Vassar Brothers Medical Center | Poughkeepsie | New York | 12601 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| UNC Chapel Hill | Chapel Hill | North Carolina | 27707 | — |
| Duke University-Duke Cancer Institute | Durham | North Carolina | 27710 | — |
| Wake Forest Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Sanford Medical Center | Fargo | North Dakota | 58122 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Womens Cancer Center/Kettering Cancer Care | Kettering | Ohio | 45429 | — |
| University of Oklahoma Health Sciences Center-Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| Willamette Valley Cancer Institute and Research Center | Eugene | Oregon | 97401 | — |
| St. Luke's University Health Network | Bethlehem | Pennsylvania | 18015 | — |
| Penn State Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| The University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| GHS Cancer Institute | Greenville | South Carolina | 29605 | — |
| Sanford Clinical Research | Sioux Falls | South Dakota | 57104 | — |
| Texas Oncology, Austin Central - USO | Austin | Texas | 78731 | — |
| Memorial Hermann | Houston | Texas | 77030 | — |
| UT Health | San Antonio | Texas | 78229 | — |
| Universtiy of Vermont | Burlington | Vermont | 05405 | — |
| MultiCare Institute for Research & Innovation | Tacoma | Washington | 98405 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
| Marshfield Clinic Cancer Care & Research Center | Marshfield | Wisconsin | 54449 | — |
| Froedtert and Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03398655, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 10, 2023 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03398655 live on ClinicalTrials.gov.