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Completed Phase 3 Interventional Results available

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Three-times Weekly Dosing in Dialysis (ASCEND-TD)

ClinicalTrials.gov ID: NCT03400033

Public ClinicalTrials.gov record NCT03400033. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 8:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized, Double-blind, Active-controlled, Parallel-group, Multi-center Study in Hemodialysis Participants With Anemia of Chronic Kidney Disease to Evaluate the Efficacy, Safety and Pharmacokinetics of Three-times Weekly Dosing of Daprodustat Compared to Recombinant Human Erythropoietin, Following a Switch From Recombinant Human Erythropoietin or Its Analogs

Study identification

NCT ID
NCT03400033
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
407 participants

Conditions and interventions

Conditions

Interventions

  • Daprodustat tablets Drug
  • Matching placebo tablets Drug
  • Epoetin alfa vials Drug
  • Saline vials or bags Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 99 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 4, 2018
Primary completion
Jun 18, 2020
Completion
Jun 18, 2020
Last update posted
Jul 11, 2021

2018 – 2020

United States locations

U.S. sites
23
U.S. states
14
U.S. cities
22
Facility City State ZIP Site status
GSK Investigational Site Mesa Arizona 85210
GSK Investigational Site Fresno California 93720
GSK Investigational Site Los Angeles California 90025
GSK Investigational Site Paramount California 90723
GSK Investigational Site Middlebury Connecticut 06762
GSK Investigational Site Hollywood Florida 33024
GSK Investigational Site Miami Florida 33169
GSK Investigational Site Tampa Florida 33614
GSK Investigational Site Macon Georgia 31201
GSK Investigational Site Meridian Idaho 83642
GSK Investigational Site Pittsfield Massachusetts 01201
GSK Investigational Site Kansas City Missouri 64111
GSK Investigational Site St Louis Missouri 63110
GSK Investigational Site Albuquerque New Mexico 87109
GSK Investigational Site College Point New York 11356
GSK Investigational Site Winston-Salem North Carolina 27103
GSK Investigational Site Oklahoma City Oklahoma 73116
GSK Investigational Site Houston Texas 77004
GSK Investigational Site Houston Texas 77099
GSK Investigational Site Lufkin Texas 75904
GSK Investigational Site Alexandria Virginia 22304
GSK Investigational Site Hampton Virginia 23666
GSK Investigational Site Norfolk Virginia 23510

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 68 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03400033, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 11, 2021 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03400033 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →