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Completed Phase 2 Interventional Results available

A Study of IMR-687 in Adult Participants With Sickle Cell Anemia (Homozygous HbSS or Sickle-β0 Thalassemia)

ClinicalTrials.gov ID: NCT03401112

Public ClinicalTrials.gov record NCT03401112. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 4:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2a, Randomised, Double-Blind, Placebo-Controlled Study of IMR-687 in Adult Patients With Sickle Cell Anaemia (Homozygous HbSS or Sickle-β0 Thalassemia)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Study of IMR-687 in adult participants with sickle cell anemia (SCA) (homozygous HbSS or sickle-β0 thalassemia).

Study identification

NCT ID
NCT03401112
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Cardurion Pharmaceuticals, Inc.
Industry
Enrollment
100 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 25, 2018
Primary completion
Aug 27, 2020
Completion
Aug 27, 2020
Last update posted
May 14, 2025

2018 – 2020

United States locations

U.S. sites
7
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
UCSF Benioff Children's Hospital Oakland Oakland California 94609
University of Connecticut Health Center Farmington Connecticut 06030
Foundation for Sickle Cell Disease Research Hollywood Florida 33021
University of Illinois Chicago Illinois 60612
Loretto Hospital Chicago Illinois 60644
Medical University of South Carolina Charleston South Carolina 29425
Baylor Scott & White Health Temple Texas 76508

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03401112, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 14, 2025 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03401112 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →