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Completed Phase 1 Interventional Accepts healthy volunteers Results available

Evaluating the Safety and Immunogenicity of Env (A,B,C,A/E)/Gag (C) DNA and gp120 (A,B,C,A/E) Protein/GLA-SE HIV Vaccines, Given Individually or Co-administered, in Healthy, HIV-1-Uninfected Adults

ClinicalTrials.gov ID: NCT03409276

Public ClinicalTrials.gov record NCT03409276. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 4:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of Polyvalent Env (A,B,C,A/E) / Gag (C) DNA and gp120 (A,B,C,A/E) Protein/GLA-SE HIV-1 Vaccines (PDPHV-201401) as a Prime-boost Regimen or Co-administered in Repeated Doses, in Healthy, HIV-1-Uninfected Adult Participants

Study identification

NCT ID
NCT03409276
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Enrollment
60 participants

Conditions and interventions

Conditions

Interventions

  • GLA-SE adjuvant Biological
  • Placebo Biological
  • env (A,B,C,A/E)/gag (C) DNA Vaccine Biological
  • gp120 (A,B,C,A/E) Protein Vaccine Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 50 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 15, 2018
Primary completion
May 10, 2020
Completion
Oct 21, 2020
Last update posted
Apr 24, 2022

2018 – 2020

United States locations

U.S. sites
6
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
Alabama CRS Birmingham Alabama 35294
The Hope Clinic of the Emory Vaccine Center CRS Decatur Georgia 30030
Fenway Health (FH) CRS Boston Massachusetts 02215-4302
University of Rochester Vaccines to Prevent HIV Infection CRS Rochester New York 14642
Case Clinical Research Site Cleveland Ohio 44106
Penn Prevention CRS Philadelphia Pennsylvania 19104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03409276, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 24, 2022 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03409276 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →