A Study to Assess the Efficacy and Safety of PPC-06 (Tepilamide Fumarate)
Public ClinicalTrials.gov record NCT03421197. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, 24-Week Study to Assess the Efficacy and Safety of PPC-06 (Tepilamide Fumarate) Extended Release Tablets in Subjects With Moderate-to-Severe Plaque Psoriasis (AFFIRM)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, double-blind, placebo-controlled, multicenter study designed to assess the safety and efficacy of PPC-06 (tepilamide fumarate) extended release in subjects with moderate-to-severe plaque psoriasis.
Study identification
- NCT ID
- NCT03421197
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 426 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 25, 2018 (Actual)
- Primary completion
- Mar 30, 2020 (Actual)
- Completion
- Mar 30, 2020 (Actual)
- Last update posted
- Apr 1, 2022
2018 – 2020
United States locations
- U.S. sites
- 74
- U.S. states
- 26
- U.S. cities
- 57
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site 144 | Glendale | Arizona | 85308 | — |
| Site 167 | Phoenix | Arizona | 85018 | — |
| Site 158 | Phoenix | Arizona | 85053 | — |
| Site 170 | Tempe | Arizona | 85283 | — |
| Site 157 | Bryant | Arkansas | 72022 | — |
| Site 125 | Rogers | Arkansas | 72758 | — |
| Site 133 | Fountain Valley | California | 92708 | — |
| Site 107 | Fremont | California | 94538 | — |
| Site 121 | Fresno | California | 93720 | — |
| Site 153 | Fullerton | California | 92835 | — |
| Site 176 | Los Angeles | California | 90057 | — |
| Site 178 | Los Angeles | California | 90057 | — |
| Site 182 | Los Angeles | California | 90057 | — |
| Site 156 | Murrieta | California | 92562 | — |
| Site 141 | San Diego | California | 92123 | — |
| Site 155 | Santa Rosa | California | 95405 | — |
| Site 137 | Clearwater | Florida | 33761 | — |
| Site 130 | Coral Gables | Florida | 33134 | — |
| Site 143 | Hialeah | Florida | 33012 | — |
| Site 145 | Hialeah | Florida | 33012 | — |
| Site 181 | Hialeah | Florida | 33012 | — |
| Site 149 | Miami | Florida | 33014 | — |
| Site 105 | Miami | Florida | 33144 | — |
| Site 174 | Miami | Florida | 33155 | — |
| Site 164 | Miami | Florida | 33175 | — |
| Site 123 | Miami | Florida | 33186 | — |
| Site 112 | Miramar | Florida | 33027 | — |
| Site 172 | New Port Richey | Florida | 34655 | — |
| Site 152 | Orange Park | Florida | 32073 | — |
| Site 154 | Pembroke Pines | Florida | 33028 | — |
| Site 110 | Sweetwater | Florida | 33172 | — |
| Site 150 | Tampa | Florida | 33609 | — |
| Site 113 | Tampa | Florida | 33624 | — |
| Site 132 | Marietta | Georgia | 30060 | — |
| Site 124 | Savannah | Georgia | 31406 | — |
| Site 122 | Nampa | Idaho | 83651 | — |
| Site 179 | Wheaton | Illinois | 60189 | — |
| Site 115 | Indianapolis | Indiana | 46256 | — |
| Site 171 | New Albany | Indiana | 47150 | — |
| Site 139 | Overland Park | Kansas | 66215 | — |
| Site 165 | Louisville | Kentucky | 40202 | — |
| Site 131 | Louisville | Kentucky | 40217 | — |
| Site 142 | Louisville | Kentucky | 40241 | — |
| Site 119 | Baton Rouge | Louisiana | 70808 | — |
| Site 126 | New Orleans | Louisiana | 70115 | — |
| Site 128 | Clinton Township | Michigan | 48038 | — |
| Site 129 | Fridley | Minnesota | 55432 | — |
| Site 111 | Kansas City | Missouri | 64114 | — |
| Site 109 | Omaha | Nebraska | 68114 | — |
| Site 127 | Las Vegas | Nevada | 89119 | — |
| Site 180- | Las Vegas | Nevada | 89148 | — |
| Site 103 | New York | New York | 10012 | — |
| Site 177 | New York | New York | 10075 | — |
| Site 104 | New York | New York | 10155 | — |
| Site 161 | Rochester | New York | 14623 | — |
| Site 146 | Stony Brook | New York | 11790 | — |
| Site 108 | High Point | North Carolina | 27262 | — |
| Site 116 | Wilmington | North Carolina | 28405 | — |
| Site 118 | Beachwood | Ohio | 44122 | — |
| Site 169 | Cincinnati | Ohio | 45236 | — |
| Site 114 | Johnston | Rhode Island | 02919 | — |
| Site 134 | Mt. Pleasant | South Carolina | 29464 | — |
| Site 100 | Rapid City | South Dakota | 57702 | — |
| Site 148 | Austin | Texas | 78745 | — |
| Site 160 | Bellaire | Texas | 77401 | — |
| Site 162 | Houston | Texas | 77004 | — |
| Site 102 | Houston | Texas | 77056 | — |
| Site 106 | San Antonio | Texas | 78229 | — |
| Site 101 | San Antonio | Texas | 78281 | — |
| Site 159 | Sugar Land | Texas | 77479 | — |
| Site 136 | Orem | Utah | 84058 | — |
| Site 166 | Norfolk | Virginia | 23507 | — |
| Site 135 | Burien | Washington | 98168 | — |
| Site 147 | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03421197, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 1, 2022 · Synced Nov 8, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03421197 live on ClinicalTrials.gov.