Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus
Public ClinicalTrials.gov record NCT03428945. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Hydroxychloroquine for Prevention of Abnormal Glucose Tolerance and Diabetes in Individuals At-risk for Type 1 Diabetes Mellitus (T1D)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study is a 2-arm, double blinded, multicenter, 2:1 randomized, placebo controlled clinical trial. Subjects will receive hydroxychloroquine or placebo and close monitoring for progression of T1D.
Study identification
- NCT ID
- NCT03428945
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 273 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 3 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 15, 2018 (Actual)
- Primary completion
- Oct 27, 2022 (Actual)
- Completion
- Oct 31, 2022 (Actual)
- Last update posted
- Apr 9, 2024
2018 – 2022
United States locations
- U.S. sites
- 37
- U.S. states
- 27
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | — |
| University of California - San Francisco | San Francisco | California | 94143 | — |
| Stanford University | Stanford | California | 94305 | — |
| Barbara Davis Center | Aurora | Colorado | 80045 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06519 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| University of Miami | Miami | Florida | 33136 | — |
| USF Diabetes Center | Tampa | Florida | 33612 | — |
| Emory Children's Center | Atlanta | Georgia | 30322 | — |
| St. Luke's Humphreys Diabetes Center | Boise | Idaho | 83702 | — |
| Rocky Mountain Clinical Research | Idaho Falls | Idaho | 83404 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Indiana University - Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kentucky/UK Healthcare | Lexington | Kentucky | 40504 | — |
| University of Louisville Pediatric Endocrinology | Louisville | Kentucky | 40202 | — |
| Joslin Diabetes Center | Boston | Massachusetts | 02215 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| The Children's Mercy Hospital | Kansas City | Missouri | 64108 | — |
| Palm Research Center, Inc. | Las Vegas | Nevada | 89148 | — |
| UBMD Pediatrics | Buffalo | New York | 14203 | — |
| Columbia University | New York | New York | 10032 | — |
| Joslin Center at SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| The University of Oklahoma | Oklahoma City | Oklahoma | 73104 | — |
| Childrens Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104-4399 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Endocrinology Specialist / Greenville Health System | Greenville | South Carolina | 29605 | — |
| GHS - Pediatric Endocrinology | Greenville | South Carolina | 29615 | — |
| Sanford Children's Specialty Clinic | Sioux Falls | South Dakota | 57105 | — |
| Vanderbilt Eskind Diabetes Clinic | Nashville | Tennessee | 37232 | — |
| University of Texas Southwestern | Dallas | Texas | 75390 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| Benaroya Research Institute | Seattle | Washington | 98101 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03428945, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 9, 2024 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03428945 live on ClinicalTrials.gov.