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Active, not recruiting Phase 3 Interventional

A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine

ClinicalTrials.gov ID: NCT03432286

Public ClinicalTrials.gov record NCT03432286. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 27, 2026, 8:24 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled Study of Galcanezumab in Patients 6 to 17 Years of Age With Episodic Migraine - the REBUILD-1 Study

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study is to evaulate the efficacy and safety of galcanezumab in participants 6 to 17 years of age for the preventive treatment of episodic migraine. The primary objective is to demonstrate the superiority of galcanezumab versus placebo in the reduction of monthly migraine headache days across the 3-month double-blind treatment period.

Study identification

NCT ID
NCT03432286
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
533 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
6 Years to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 14, 2018 (Actual)
Primary completion
Nov 14, 2025 (Actual)
Completion
Nov 2026 (Estimated)
Last update posted
Jan 26, 2026

2018 – 2026

United States locations

U.S. sites
38
U.S. states
22
U.S. cities
36
Facility City State ZIP Site status
Rehabilitation & Neurological Services Huntsville Alabama 35805 —
21st Century Neurology, a Division of Xenoscience, Inc. Phoenix Arizona 85004 —
Phoenix Children's Hospital Phoenix Arizona 85016 —
Center for Neurosciences Tucson Arizona 85718 —
Miller Children's & Women's Hospital Long Beach Long Beach California 90806 —
Wr-McCr, Llc San Diego California 92108 —
Children's Hospital Colorado Aurora Colorado 80045 —
Clinical Neuroscience Solutions, Inc. dba CNS Healthcare Jacksonville Florida 32256 —
University of Miami Don Suffer Clinical Research Building Miami Florida 33136 —
Ezy Medical Research Miami Lakes Florida 33015 —
Clinical Neuroscience Solutions Orlando Florida 32801 —
Avanza Medical Research Center Pensacola Florida 32503 —
USF Health Tampa Florida 33612 —
Premiere Research Institute at Palm Beach Neurology West Palm Beach Florida 33407 —
Clinical Integrative Research Center of Atlanta, LLC Atlanta Georgia 30328 —
Meridian Clinical Research, LLC Savannah Georgia 31406 —
Medical Research Partners Ammon Idaho 83406 —
Elite Clinical Trials Blackfoot Idaho 83221 —
Northwest Clinical Trials Boise Idaho 83704 —
Inpatient Pharmacy Hoffman Estates Illinois 60169 —
University of Kentucky Chandler Medical Center Lexington Kentucky 40536 —
Pharmasite Research, Inc. Baltimore Maryland 21208 —
Boston Clinical Trials Boston Massachusetts 02131 —
MedVadis Research Corporation Waltham Massachusetts 02451 —
Minneapolis Clinic of Neurology - Burnsville Office Burnsville Minnesota 55337 —
Children Mercy Pediatric Clinical Research Unit Kansas City Missouri 64108 —
Dent Neurologic Institute Amherst New York 14226 —
Cohen Children's Northwell Health Physician Partners - Pediatric Neurology New Hyde Park New York 11042 —
Velocity Clinical Research at Raleigh Neurology Raleigh North Carolina 27607 —
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 —
Providence Health & Services Portland Oregon 97225 —
UPMC Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15224 —
Office 18 Pittsburgh Pennsylvania 15236 —
Velocity Clinical Research, Providence East Greenwich Rhode Island 02818 —
Tribe Clinical Research, LLC Greenville South Carolina 29607 —
Pain and Headache Centers of Texas Houston Texas 77054 —
Northwest Clinical Research Center Bellevue Washington 98007 —
Seattle Children's Hospital Seattle Washington 98105 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03432286, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 26, 2026 · Synced Oct 27, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03432286 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →