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Completed Phase 2 Interventional Accepts healthy volunteers

Study of Efficacy, Cycle Control, and Safety of a NES-E2 Contraceptive Vaginal Ring

ClinicalTrials.gov ID: NCT03432416

Public ClinicalTrials.gov record NCT03432416. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 4, 2026, 2:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Open-label Randomized Study on the Efficacy, Cycle Control and Safety of a Contraceptive Vaginal Ring Delivering a Daily Dose of Nestorone® and Estradiol (NES-E2 CVR).

Study identification

NCT ID
NCT03432416
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Premier Research
Other
Enrollment
385 participants

Conditions and interventions

Interventions

  • NES-E2 CVR Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 35 Years
Sex
Female
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 11, 2018
Primary completion
Aug 27, 2021
Completion
Dec 13, 2021
Last update posted
Oct 30, 2025

2018 – 2021

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
10
Facility City State ZIP Site status
Essential Access Health Los Angeles California 30010
University of California, Davis Sacramento California 95817
University of Colorado Denver Aurora Colorado 80045
Johns Hopkins Bayview Medical Center Baltimore Maryland 21224
Bellevue Hospital Center New York New York 10016
Columbia University New York New York 10032
University of Cincinnati Cincinnati Ohio 45267
Oregon Health Science University Portland Oregon 97239
University of Pennsylvania School of Medicine Philadelphia Pennsylvania 19104
University of Utah Salt Lake City Utah 84132
Eastern Virginia Medical School Norfolk Virginia 23507

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03432416, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 30, 2025 · Synced May 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03432416 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →