Safety and Efficacy of ADS-5102 in Multiple Sclerosis Patients With Walking Impairment
Public ClinicalTrials.gov record NCT03436199. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 3-arm, Multicenter, Double-blind, Placebo-controlled, Randomized Study to Assess the Efficacy and Safety of ADS-5102 Amantadine Extended Release Capsules in Multiple Sclerosis Patients With Walking Impairment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study assessed the efficacy and safety of ADS-5102 (at daily doses of 137 mg or 274 mg) compared with placebo in MS patients with walking impairment.
Study identification
- NCT ID
- NCT03436199
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 558 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 29, 2018 (Actual)
- Primary completion
- Dec 10, 2019 (Actual)
- Completion
- Dec 10, 2019 (Actual)
- Last update posted
- Dec 21, 2021
2018 – 2019
United States locations
- U.S. sites
- 78
- U.S. states
- 32
- U.S. cities
- 76
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Adamas Clinical Site | Cullman | Alabama | 35058 | — |
| Adamas Clinical Site | Phoenix | Arizona | 85032 | — |
| Adamas Clinical Site | Scottsdale | Arizona | 85251 | — |
| Adamas Clinical Site | Tucson | Arizona | 85704 | — |
| Adamas Clinical Site | Carlsbad | California | 92011 | — |
| Adamas Clinical Site | Fresno | California | 93710 | — |
| Adamas Clinical Site | Fullerton | California | 92835 | — |
| Adamas Clinical Site | Long Beach | California | 90806 | — |
| Adamas Clinical Site | Newport Beach | California | 92663 | — |
| Adamas Clinical Site | Sacramento | California | 95817 | — |
| Adamas Clinical Site | Aurora | Colorado | 80045 | — |
| Adamas Clinical Site | Colorado Springs | Colorado | 80907 | — |
| Adamas Clinical Site | Denver | Colorado | 80209 | — |
| Adamas Clinical Site | Fort Collins | Colorado | 80528 | — |
| Adamas Clinical Site | Fairfield | Connecticut | 06824 | — |
| Adamas Clinical Site | New London | Connecticut | 06320 | — |
| Adamas Clinical Site | Washington D.C. | District of Columbia | 20007 | — |
| Adamas Clinical Site | Maitland | Florida | 32751 | — |
| Adamas Clinical Site | Miami | Florida | 33136 | — |
| Adamas Clinical Site | Naples | Florida | 34105 | — |
| Adamas Clinical Site | Orlando | Florida | 32806 | — |
| Adamas Clinical Site | Ormond Beach | Florida | 32174 | — |
| Adamas Clinical Site | Palm Coast | Florida | 32164 | — |
| Adamas Clinical Site | Port Charlotte | Florida | 33952 | — |
| Adamas Clinical Site | Sarasota | Florida | 34233 | — |
| Adamas Clinical Site | Tampa | Florida | 33609 | — |
| Adamas Clinical Site | Vero Beach | Florida | 32960 | — |
| Adamas Clinical Site | Atlanta | Georgia | 30309 | — |
| Adamas Clinical Site | Savannah | Georgia | 31406 | — |
| Adamas Clinical Site | Northbrook | Illinois | 60062 | — |
| Adamas Clinical Site | Indianapolis | Indiana | 46256 | — |
| Adamas Clinical Site | Kansas City | Kansas | 66160 | — |
| Adamas Clinical Site | Lenexa | Kansas | 66214 | — |
| Adamas Clinical Site | Overland Park | Kansas | 66212 | — |
| Adamas Clinical Site | Foxborough | Massachusetts | 02035 | — |
| Adamas Clinical Site | Lexington | Massachusetts | 02421 | — |
| Admas Clinical Site | Detroit | Michigan | 48201 | — |
| Adamas Clinical Site | Farmington Hills | Michigan | 48334 | — |
| Adamas Clinical Site | Golden Valley | Minnesota | 55422 | — |
| Adamas Clinical Site | Kansas City | Missouri | 64111 | — |
| Adamas Clinical Site | St Louis | Missouri | 63110 | — |
| Adamas Clinical Site | Great Falls | Montana | 59405 | — |
| Adamas Clinical Site | Lincoln | Nebraska | 68506 | — |
| Adamas Clinical Site | Omaha | Nebraska | 68198 | — |
| Adamas Clinical Site | Las Vegas | Nevada | 89016 | — |
| Adamas Clinical Site | Albuquerque | New Mexico | 87131 | — |
| Adamas Clinical Site | Amherst | New York | 14226 | — |
| Adamas Clinical Site | Lake Success | New York | 11042 | — |
| Adamas Clinical Site | New York | New York | 10029 | — |
| Adamas Clinical Site | Patchogue | New York | 11772 | — |
| Adamas Clinical Site | Plainview | New York | 11803 | — |
| Adamas Clinical Site | Rochester | New York | 14642 | — |
| Adamas Clinical Site | Staten Island | New York | 10306 | — |
| Adamas Clinical Site | Charlotte | North Carolina | 28207 | — |
| Adamas Clinical Site | Raleigh | North Carolina | 27607 | — |
| Adamas Clinical Site | Centerville | Ohio | 45459 | — |
| Adamas Clinical Site | Cleveland | Ohio | 44195 | — |
| Adamas Clinical Site | Columbus | Ohio | 43214 | — |
| Adamas Clinical Site | Oklahoma City | Oklahoma | 73104 | — |
| Adamas Clinical Site | Portland | Oregon | 97225 | — |
| Adamas Clinical Site | Philadelphia | Pennsylvania | 19140 | — |
| Adamas Clinical Site | Charleston | South Carolina | 29406 | — |
| Adamas Clinical Site | Greer | South Carolina | 29650 | — |
| Adamas Clinical Site | Old Point Station | South Carolina | 29707 | — |
| Adamas Clinical Site | Spartanburg | South Carolina | 29307 | — |
| Adamas Clinical Site | Cordova | Tennessee | 38018 | — |
| Adamas Clinical Site | Franklin | Tennessee | 37064 | — |
| Adamas Clinical Site | Johnson City | Tennessee | 37604 | — |
| Adamas Clinical Site | Houston | Texas | 77030 | — |
| Adamas Clinical Site | Houston | Texas | 77074 | — |
| Adamas Clinical Site | Round Rock | Texas | 78681 | — |
| Adamas Clinical Site | Salt Lake City | Utah | 84103 | — |
| Adamas Clinical Site | Newport News | Virginia | 23601 | — |
| Adamas Clinical Site | Norfolk | Virginia | 23502 | — |
| Adamas Clinical Site | Kirkland | Washington | 98034 | — |
| Adamas Clinical Site | Seattle | Washington | 98101 | — |
| Adamas Clinical Site | Seattle | Washington | 98122 | — |
| Adamas Clinical Site | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03436199, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 21, 2021 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03436199 live on ClinicalTrials.gov.