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Completed Phase 1 Interventional

Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma

ClinicalTrials.gov ID: NCT03440567

Public ClinicalTrials.gov record NCT03440567. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 8:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I Study of Avelumab Plus Utomilumab-Based Combination Therapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Mantle Cell Lymphoma

Study identification

NCT ID
NCT03440567
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
City of Hope Medical Center
Other
Enrollment
16 participants

Conditions and interventions

Interventions

  • Autologous Hematopoietic Stem Cell Transplantation Procedure
  • Avelumab Drug
  • Carboplatin Drug
  • Etoposide Phosphate Drug
  • Ibrutinib Drug
  • Ifosfamide Drug
  • Laboratory Biomarker Analysis Other
  • Rituximab Biological
  • Utomilumab Biological

Procedure · Drug · Other + 1 more

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 1, 2018
Primary completion
Jun 25, 2024
Completion
Jun 25, 2024
Last update posted
Mar 25, 2025

2018 – 2024

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
City of Hope Medical Center Duarte California 91010

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03440567, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 25, 2025 · Synced May 16, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03440567 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →