A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)
Public ClinicalTrials.gov record NCT03442764. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Concentration-guided, Exploratory Study of Mavacameten in Patients With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM) and Preserved Left Ventricular Ejection Fraction
Study identification
- NCT ID
- NCT03442764
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- MyoKardia, Inc.
- Industry
- Enrollment
- 59 participants
Conditions and interventions
Conditions
Interventions
- mavacamten Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 29, 2018
- Primary completion
- Jan 6, 2020
- Completion
- Jan 6, 2020
- Last update posted
- Aug 8, 2022
2018 – 2020
United States locations
- U.S. sites
- 32
- U.S. states
- 20
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| Cedars-Sinai Medical Center (Smidt Heart Institute) | Los Angeles | California | 90048 | — |
| Stanford Hospital and Clinics/Stanford University | Palo Alto | California | 94305 | — |
| University of California, San Francisco | San Francisco | California | 94143 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06520 | — |
| Northwestern University | Evanston | Illinois | 60208 | — |
| St. Vincent Medical Group | Indianapolis | Indiana | 46260 | — |
| University of Iowa Hospitals and clinics | Iowa City | Iowa | 52242 | — |
| University of Maryland Medical System | Baltimore | Maryland | 21201 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Michigan Medicine | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| NYU Winthrop Hospital | Mineola | New York | 11501 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28203 | — |
| Duke Cardiology at Southpoint | Durham | North Carolina | 27713 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| St. Luke's Cardiology Associates | Bethlehem | Pennsylvania | 18018 | — |
| Penn State Health Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| The University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390-9034 | — |
| Baylor St. Luke Medical Center at Houston, Texas Heart Institute Out-patient Clinic | Houston | Texas | 77030 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| University of Utah Medical Center | Salt Lake City | Utah | 84132 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Unity Point Health Meriter Heart and Vascular Institute | Madison | Wisconsin | 53713 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03442764, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 8, 2022 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03442764 live on ClinicalTrials.gov.