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Completed Phase 2 Interventional Results available

A Study to Evaluate the Efficacy and Safety of MIN-117 in Adult Patients With Major Depressive Disorder

ClinicalTrials.gov ID: NCT03446846

Public ClinicalTrials.gov record NCT03446846. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 11:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Parallel-Group, Placebo Controlled Study to Evaluate the Efficacy and Safety of 2 Fixed Doses (5.0 mg or 2.5 mg) of MIN-117 in Adult Patients With Major Depressive Disorder

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

MIN-117C03 is a 6-week, 3-arm, randomized, double-blind, placebo controlled study to investigate the safety and efficacy of MIN-117 in male and female patients with Major Depressive Disorder, aged 18 to 65 years. Approximately 324 patients were to be randomly assigned to 1 of 3 treatment arms, including placebo, 2.5 mg MIN-117, or 5.0 mg MIN-117, in a 2:1:1 ratio.

Study identification

NCT ID
NCT03446846
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Minerva Neurosciences
Industry
Enrollment
360 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 29, 2018
Primary completion
Nov 20, 2019
Completion
Dec 12, 2019
Last update posted
Dec 16, 2020

2018 – 2019

United States locations

U.S. sites
10
U.S. states
8
U.S. cities
10
Facility City State ZIP Site status
Woodland International Research Group, LLC Little Rock Arkansas 72211
Collaborative Neuroscience Network, LLC Garden Grove California 92845
Collaborative Neuroscience Network, LLC Torrance California 90502
Pacific Clinical Research Medical Group Upland California 91786
Atlanta Center for Medical Research Atlanta Georgia 30331
Hassman Research Institute, LLC Berlin New Jersey 08009
Neurobehavioral Research, Inc, Cedarhurst, NY Cedarhurst New York 11516
Neuro-Behavorial Clinical Research Inc Canton Ohio 44718
Oregon Center for Clinical Investigations Portland Oregon 97214
FutureSearch Trials Dallas Texas 75231

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03446846, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 16, 2020 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03446846 live on ClinicalTrials.gov.

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