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Terminated Phase 2 Interventional Results available

A Study to Evaluate PF-06730512 in Adults With Focal Segmental Glomerulosclerosis (FSGS)

ClinicalTrials.gov ID: NCT03448692

Public ClinicalTrials.gov record NCT03448692. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 2, 2026, 5:15 PM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 2, 24-WEEK, ADAPTIVE, OPEN LABEL, SEQUENTIAL COHORT TRIAL TO EVALUATE THE EFFICACY, SAFETY, TOLERABILITY AND PHARMACOKINETICS OF PF-06730512 FOLLOWING MULTIPLE DOSES IN ADULT SUBJECTS WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS (FSGS)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this Phase 2 adaptive study is to evaluate the efficacy, safety, tolerability and pharmacokinetics of PF-06730512 following multiple intravenous infusions in adult subjects with FSGS.

Study identification

NCT ID
NCT03448692
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
47 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 15, 2018 (Actual)
Primary completion
Feb 14, 2023 (Actual)
Completion
Feb 14, 2023 (Actual)
Last update posted
Apr 18, 2024

2018 – 2023

United States locations

U.S. sites
56
U.S. states
14
U.S. cities
20
Facility City State ZIP Site status
The Kirklin Clinic of University Alabama Birmingham Hospital Birmingham Alabama 35233 —
Investigational Drug Service Pharmacy UAB Hosptial Birmingham Alabama 35249 —
Clinical Research Unit at UAB Hospital Birmingham Alabama 35294 —
UAB Nephrology Research Clinic at Paula Building Birmingham Alabama 35294 —
Academic Medical Research Institute Los Angeles California 90022 —
Cedars Sinai Medical Center Los Angeles California 90048 —
Cedars-Sinai Ambulatory Infusion Center Los Angeles California 90048 —
Cedars-Sinai Comprehensive Transplant Center Los Angeles California 90048 —
Ronald Reagan UCLA Medical Center Los Angeles California 90095 —
UCLA Clinical and Translational Research Center Los Angeles California 90095 —
UCLA Department of Medicine Los Angeles California 90095 —
Clinical and Translation Research Unit Palo Alto California 94304 —
Stanford University-Nephrology Division Palo Alto California 94304 —
University of California, San Francisco San Francisco California 94143 —
Stanford Health Care Investigational Pharmacy Stanford California 94305 —
Stanford University-Nephrology Division Stanford California 94305 —
Stanford University Stanford California 94305 —
Yale Center for Clinical Investigation Hospital Research Unit New Haven Connecticut 06510 —
Yale Nephrology Clinical Research Clinic New Haven Connecticut 06510 —
Yale University School of Medicine - Yale-New Haven Hospital New Haven Connecticut 06510 —
Yale University New Haven Connecticut 06510 —
Yale New Haven Hospital New Haven Connecticut 06511 —
Yale Center for Clinical Investigation - Church Street Research Unit New Haven Connecticut 06519 —
University of Miami Hospital and Clinics Miami Florida 33136 —
University of Miami Katz Family Division of Nephrology Miami Florida 33136 —
University of Miami Miami Florida 33136 —
Georgia Nephrology Research Institute Lawrenceville Georgia 30046 —
Georgia Nephrology Lawrenceville Georgia 30046 —
University of Iowa Hospitals and Clinics Iowa City Iowa 52242 —
Johnson County Clin Trials Lenexa Kansas 66219 —
Boston Medical Center - Interventional Radiology Boston Massachusetts 02118 —
Boston Medical Center - Nephrology Boston Massachusetts 02118 —
Boston Medical Center Boston Massachusetts 02118 —
Boston University - GCRU Boston Massachusetts 02118 —
Henry Ford Hospital Detroit Michigan 48202 —
Clinical Research Consultants, LLC Kansas City Missouri 64111 —
St. Luke's Hospital Kansas City Missouri 64111 —
New York University Grossman School of Medicine - CTSI New York New York 10016 —
UNC Eastowne Chapel Hill North Carolina 27514 —
UNC Clinical and Translational Research Center Chapel Hill North Carolina 27599-7064 —
University of Cincinnati at DCI McMillan Research Unit Cincinnati Ohio 45206 —
Hoxworth Center Subspecialties Clinic Cincinnati Ohio 45219 —
UC Health Barrett Center Cincinnati Ohio 45219 —
UC Health Medical Arts Building Cincinnati Ohio 45219 —
University of Cincinnati Gardner Neuroscience Institute Cincinnati Ohio 45229 —
The Cleveland Clinic - Investigational Drug Pharmacy Cleveland Ohio 44195 —
The Cleveland Clinic Cleveland Ohio 44195 —
CarePoint East at The Ohio State University Columbus Ohio 43203 —
The Ohio State University Clinical Research Center Columbus Ohio 43210 —
The Ohio State University Investigational Drug Services Columbus Ohio 43210 —
The Ohio State University Wexner Medical Center- Nephrology Clinical Trials Unit Columbus Ohio 43210 —
The Ohio State University Columbus Ohio 43210 —
Kidney and Hypertension Care Center, PA Houston Texas 77004 —
Southside Pharmacy Houston Texas 77030 —
Prolato Clinical Research Center (PCRC) Houston Texas 77054 —
Baylor Scott & White Clinic - Temple South Loop Temple Texas 76502 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 54 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03448692, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 18, 2024 · Synced Nov 2, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03448692 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →