A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-027)
Public ClinicalTrials.gov record NCT03449134. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 12-Month Study to Evaluate the Efficacy and Safety of MK-7264 in Adult Participants With Chronic Cough (PN027)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main objectives of this study will be to evaluate the efficacy of gefapixant in reducing cough frequency as measured over a 24-hour period at Week 12, and to evaluate the safety and tolerability of gefapixant. The primary hypothesis is that at least one gefapixant dose is superior to placebo in reducing coughs per hour (over 24 hours) at Week 12.
Study identification
- NCT ID
- NCT03449134
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 732 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 14, 2018 (Actual)
- Primary completion
- Jun 5, 2020 (Actual)
- Completion
- Aug 17, 2020 (Actual)
- Last update posted
- Jun 16, 2021
2018 – 2020
United States locations
- U.S. sites
- 27
- U.S. states
- 15
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Solutions of Arizona PC ( Site 0036) | Litchfield Park | Arizona | 85340 | — |
| Medical Research of AZ ( Site 0060) | Scottsdale | Arizona | 85251 | — |
| Biosolutions Clinical Research Center ( Site 0070) | La Mesa | California | 91942 | — |
| Center for Clinical Trials, LLC ( Site 0059) | Paramount | California | 90723 | — |
| Sher Allergy Specialists/Center For Cough ( Site 0078) | Largo | Florida | 33778 | — |
| Well Pharma Medical Research, Corp. ( Site 0093) | Miami | Florida | 33143 | — |
| Florida Pulmonary Research Institute, LLC ( Site 0019) | Winter Park | Florida | 32789 | — |
| Midwest Allergy Sinus Asthma, SC ( Site 0081) | Normal | Illinois | 61761 | — |
| Cotton-O'Neil Clinical Research Center ( Site 0052) | Topeka | Kansas | 66606 | — |
| BreatheAmerica Inc ( Site 0048) | Shreveport | Louisiana | 71106 | — |
| Clinical Research Institute LLC ( Site 0004) | Minneapolis | Minnesota | 55402 | — |
| The Center for Pharmaceutical Research PC ( Site 0016) | Kansas City | Missouri | 64114 | — |
| American Health Research ( Site 0082) | Charlotte | North Carolina | 28207 | — |
| Clinical Research of Gastonia ( Site 0043) | Gastonia | North Carolina | 28054 | — |
| Bernstein Clinical Research Center, LLC ( Site 0005) | Cincinnati | Ohio | 45231 | — |
| Vital Prospects Clinical Research Institute, PC ( Site 0037) | Tulsa | Oklahoma | 74136 | — |
| Asthma Nasal Disease & Allergy Research Center of New England ( Site 0075) | East Providence | Rhode Island | 02914 | — |
| Sirius Clinical Research, LLC ( Site 0102) | Austin | Texas | 78759 | — |
| Pharmaceutical Research & Consulting, Inc. ( Site 0029) | Dallas | Texas | 75231 | — |
| Mainland Medical Research Institute ( Site 0003) | Dickinson | Texas | 77539 | — |
| Diagnostics Research Group ( Site 0035) | San Antonio | Texas | 78229 | — |
| Allergy & Asthma Center ( Site 0001) | Waco | Texas | 76712 | — |
| Intermountain Clinical Research ( Site 0033) | Draper | Utah | 84020 | — |
| Charlottesville Medical Research Center, LLC ( Site 0006) | Charlottesville | Virginia | 22911 | — |
| Pulmonary Associates of Richmond Inc. ( Site 0101) | Richmond | Virginia | 23225 | — |
| National Clinical Research-Richmond, Inc. ( Site 0073) | Richmond | Virginia | 23294 | — |
| Lung and Sleep Specialists ( Site 0091) | Williamsburg | Virginia | 23188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 129 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03449134, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 16, 2021 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03449134 live on ClinicalTrials.gov.