A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-030)
Public ClinicalTrials.gov record NCT03449147. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 12-Month Study to Evaluate the Efficacy and Safety of MK-7264 in Adult Participants With Chronic Cough (PN030)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objectives of this study are to evaluate the efficacy of gefapixant (MK-7264) in reducing cough frequency as measured over a 24-hour period, and to determine the safety and tolerability of gefapixant. The primary hypothesis is that at least one dose of gefapixant is superior to placebo in reducing coughs per hour (over 24 hours) at Week 24.
Study identification
- NCT ID
- NCT03449147
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,317 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 15, 2018 (Actual)
- Primary completion
- Aug 20, 2020 (Actual)
- Completion
- Oct 30, 2020 (Actual)
- Last update posted
- Sep 2, 2021
2018 – 2020
United States locations
- U.S. sites
- 34
- U.S. states
- 23
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Medical Group ( Site 0022) | Peoria | Arizona | 85381 | — |
| Pulmonary Associates, PA ( Site 0063) | Phoenix | Arizona | 85006 | — |
| Clinical Research Consortium ( Site 0088) | Tempe | Arizona | 85283 | — |
| Allergy & Asthma Associates of SCV Research Center ( Site 0064) | San Jose | California | 95117 | — |
| Lenus Research & Medical Group Llc ( Site 0075) | Sweetwater | Florida | 33172 | — |
| Atlanta Allergy & Asthma Clinic PA ( Site 0029) | Stockbridge | Georgia | 30281 | — |
| Rush University Medical Center ( Site 0103) | Chicago | Illinois | 60612 | — |
| Healthcare Research Network LLC ( Site 0093) | Flossmoor | Illinois | 60422 | — |
| Abraham Research, PLLC ( Site 0107) | Fort Mitchell | Kentucky | 41017 | — |
| Paul A. Shapero, MD ( Site 0104) | Bangor | Maine | 04401 | — |
| Bethesda Allergy Asthma and Research Center LLC ( Site 0019) | Bethesda | Maryland | 20814 | — |
| Respiratory Medicine Research Institute of Michigan, PLC ( Site 0034) | Ypsilanti | Michigan | 48197 | — |
| Minnesota Lung Center ( Site 0108) | Edina | Minnesota | 55435 | — |
| Mayo Clinic - Rochester ( Site 0006) | Rochester | Minnesota | 55905 | — |
| Minnesota Lung Center ( Site 0041) | Woodbury | Minnesota | 55125 | — |
| The Lung Research Center ( Site 0072) | Chesterfield | Missouri | 63017 | — |
| University of Missouri ENT & Allergy Center ( Site 0066) | Columbia | Missouri | 65201 | — |
| CHI Health Creighton University Medical Center ( Site 0024) | Omaha | Nebraska | 68134 | — |
| Clinical Research Consortium ( Site 0050) | Las Vegas | Nevada | 89109 | — |
| Atlantic Research Center LLC ( Site 0012) | Ocean City | New Jersey | 07712 | — |
| Albuquerque Clinical Trials ( Site 0039) | Albuquerque | New Mexico | 87102 | — |
| Montefiore Medical Center ( Site 0098) | The Bronx | New York | 10461 | — |
| Wake Research Associates, LLC ( Site 0058) | Raleigh | North Carolina | 27612 | — |
| Remington-Davis, Inc. ( Site 0082) | Columbus | Ohio | 43215 | — |
| Clinical Research Institute of Southern Oregon, PC ( Site 0099) | Medford | Oregon | 97504 | — |
| Allergy Associates Research Center ( Site 0026) | Portland | Oregon | 97202 | — |
| AAPRI Clinical Research Institute ( Site 0001) | Warwick | Rhode Island | 02886 | — |
| Lowcountry Lung & Critical Care, PA ( Site 0045) | Charleston | South Carolina | 29406 | — |
| Allergic Disease and Asthma Center ( Site 0043) | Greenville | South Carolina | 29607 | — |
| Clinical Research of Rock Hill ( Site 0079) | Rock Hill | South Carolina | 29732 | — |
| Clinical Research Partners, LLC. ( Site 0080) | Richmond | Virginia | 23235 | — |
| Bellingham Asthma & Allergy ( Site 0076) | Bellingham | Washington | 98225 | — |
| Marycliff Clinical Research ( Site 0062) | Spokane | Washington | 99202 | — |
| Multicare Health System ( Site 0018) | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 137 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03449147, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 2, 2021 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03449147 live on ClinicalTrials.gov.