PRIMEx - A Study of 2 Doses of Oral CXA-10 in Pulmonary Arterial Hypertension (PAH)
Public ClinicalTrials.gov record NCT03449524. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2 Multicenter, Double-Blind, Placebo Controlled, Efficacy, Safety, and Pharmacokinetic Study of 2 Doses of CXA-10 on Stable Background Therapy in Subjects With Pulmonary Arterial Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter double-blind, placebo-controlled study to evaluate the safety, efficacy and pharmacokinetics of 2 doses of CXA-10 on stable background therapy in 96 subjects 18 to 80 years of age with PAH.
Study identification
- NCT ID
- NCT03449524
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 69 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 1, 2018 (Actual)
- Primary completion
- Aug 5, 2020 (Actual)
- Completion
- Aug 5, 2020 (Actual)
- Last update posted
- Aug 10, 2020
2018 – 2020
United States locations
- U.S. sites
- 40
- U.S. states
- 23
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35233 | — |
| Arizona Pulmonary Specialists | Phoenix | Arizona | 85012 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| University of California San Francisco | San Francisco | California | 94143-2202 | — |
| University of Colorado Health | Aurora | Colorado | 80045 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Washington Hospital (Medstar) | Washington D.C. | District of Columbia | 20010 | — |
| George Washington Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | — |
| University of Florida Health | Gainesville | Florida | 32608 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| University of Miami | Miami | Florida | 33136 | — |
| AdventHealth | Orlando | Florida | 32803 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Loyola University | Maywood | Illinois | 60153-3328 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas | Kansas City | Kansas | 66160 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115-6110 | — |
| University of Minnesotta | Minneapolis | Minnesota | 55455 | — |
| Washington University and Barnes Jewish Hospital | St Louis | Missouri | 63110 | — |
| University of New Mexico Health Sciences Center | Albuquerque | New Mexico | 87131 | — |
| NYU Langone Medical Center | New York | New York | 10279 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| Christ Hospital-Lindner Research Center | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| INTEGRIS Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| Penn State M.S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Vanderbuilt University | Nashville | Tennessee | 37232 | — |
| UT Southwestern | Dallas | Texas | 75390 | — |
| Texas Tech | El Paso | Texas | 79905 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| University of Virginia School of Medicine | Charlottesville | Virginia | 22908 | — |
| Inova Medical Campus | Falls Church | Virginia | 22042 | — |
| Sentara Medical Group | Norfolk | Virginia | 23507 | — |
| Froedert Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03449524, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 10, 2020 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03449524 live on ClinicalTrials.gov.