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Completed Phase 2 Interventional Results available

Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies

ClinicalTrials.gov ID: NCT03453619

Public ClinicalTrials.gov record NCT03453619. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 3:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study to Evaluate the Safety and Biologic Activity of APL- 2 in Patients With IgA Nephropathy, Lupus Nephritis, Primary Membranous Nephropathy, or C3 Glomerulopathy (C3 Glomerulonephritis and Dense Deposit Disease)

Study identification

NCT ID
NCT03453619
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Apellis Pharmaceuticals, Inc.
Industry
Enrollment
21 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 25, 2018
Primary completion
Apr 15, 2020
Completion
Aug 25, 2023
Last update posted
Feb 12, 2025

2018 – 2023

United States locations

U.S. sites
17
U.S. states
14
U.S. cities
17
Facility City State ZIP Site status
Stanford University Stanford California 94305
Children's Hospital Colorado Aurora Colorado 80045
HealthONE Physician Care, Rocky Mountain Hospital for Children Denver Colorado 80205
Washington Nephrology Associates Washington D.C. District of Columbia 20037
Horizon Research Group Coral Gables Florida 33134
Emory University Atlanta Georgia 30322
American Research LLC Jeffersonville Indiana 47130
Northwest Louisiana Nephrology LLC Shreveport Louisiana 71101
Washington Nephrology Associates Takoma Park Maryland 20912
Clinical Research Consultants Kansas City Missouri 64111
Davita Clinical Research The Bronx New York 10461
Westchester Medical Center Valhalla New York 10595
Southeastern Nephrology Associates Wilmington North Carolina 28401
University Clinical Health Memphis Tennessee 38103
Washington Nephrology Associates Alexandria Virginia 22304
Davita Clinical Research Chesapeake Virginia 23320
Milwaukee Nephrologists Wauwatosa Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03453619, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 12, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03453619 live on ClinicalTrials.gov.

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