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Completed Phase 2 Interventional Results available

Study of AG10 in Amyloid Cardiomyopathy

ClinicalTrials.gov ID: NCT03458130

Public ClinicalTrials.gov record NCT03458130. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 8:12 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Placebo-controlled, Dose-ranging Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AG10 in Patients With Symptomatic Transthyretin Amyloid Cardiomyopathy

Study identification

NCT ID
NCT03458130
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eidos Therapeutics, a BridgeBio company
Industry
Enrollment
49 participants

Conditions and interventions

Interventions

  • AG10 Drug
  • Placebo Oral Tablet Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 90 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 26, 2018
Primary completion
Oct 4, 2018
Completion
Oct 4, 2018
Last update posted
Nov 15, 2022

2018

United States locations

U.S. sites
13
U.S. states
10
U.S. cities
12
Facility City State ZIP Site status
Cedars-Sinai Medical Center Beverly Hills California 90211
Stanford University Palo Alto California 94304
University of California San Francisco San Francisco California 94143
Yale University New Haven Connecticut 06520
Northwestern University Chicago Illinois 60611
Brigham and Women's Hospital Boston Massachusetts 02115
Boston University Boston Massachusetts 02127
Mayo Clinic Rochester Minnesota 55905
Columbia University New York New York 10032
Cleveland Clinic Cleveland Ohio 44195
Oregon Health & Science University Portland Oregon 97239
Medical University of South Carolina Charleston South Carolina 29424
University of Utah Salt Lake City Utah 84132

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03458130, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 15, 2022 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03458130 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →