Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Public ClinicalTrials.gov record NCT03470545. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double Blind, Placebo Controlled Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Study identification
- NCT ID
- NCT03470545
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- MyoKardia, Inc.
- Industry
- Enrollment
- 251 participants
Conditions and interventions
Conditions
Interventions
- mavacamten Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 28, 2018
- Primary completion
- Mar 13, 2020
- Completion
- May 5, 2020
- Last update posted
- Oct 3, 2021
2018 – 2020
United States locations
- U.S. sites
- 29
- U.S. states
- 19
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| Cedars-Sinai Medical Center (Smidt Heart Institute) | Los Angeles | California | 90048 | — |
| UCSF School of Medicine | San Francisco | California | 94143 | — |
| Stanford University | Stanford | California | 94305 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 16511 | — |
| Mayo Clinic Jacksonville - PPDS | Jacksonville | Florida | 32224 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University Of Iowa Hospitals And Clinics | Iowa City | Iowa | 52242 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Spectrum Health | Grand Rapids | Michigan | 49512 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| NYU Langone Medical Center | New York | New York | 10017 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28203 | — |
| Duke Cardiology at Southpoint | Durham | North Carolina | 27710 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| St. Luke's Cardiology Associates | Bethlehem | Pennsylvania | 18018 | — |
| University of Pennsylvania (Penn Heart and Vascular Center) | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| Methodist University Hospital | Memphis | Tennessee | 38163 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75235 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| University of Texas Houston Medical School | Houston | Texas | 77030 | — |
| Intermountain Medical Center | Salt Lake City | Utah | 84107 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22903 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03470545, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 3, 2021 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03470545 live on ClinicalTrials.gov.