ClinicalTrials.gov record
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome
ClinicalTrials.gov ID: NCT03473223
Public ClinicalTrials.gov record NCT03473223. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 12, 2026, 8:09 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects With Acute Coronary Syndrome
Study identification
- NCT ID
- NCT03473223
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- CSL Behring
- Industry
- Enrollment
- 18,226 participants
Conditions and interventions
Conditions
Interventions
- Apolipoprotein A-I [human] (apoA-I) Biological
- Placebo Other
Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 20, 2018
- Primary completion
- Feb 15, 2023
- Completion
- Nov 16, 2023
- Last update posted
- Jan 13, 2025
2018 – 2023
United States locations
- U.S. sites
- 202
- U.S. states
- 42
- U.S. cities
- 178
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| 8400896 - Advanced Cardiovascular LLC | Alexander City | Alabama | 35010 | — |
| 8400350 - Cardiology, PC | Birmingham | Alabama | 35211 | — |
| 8400337 - Heart Center Research, LLC | Huntsville | Alabama | 35801 | — |
| 8400713 - University of South Alabama College of Medicine | Mobile | Alabama | 36617 | — |
| 8400556 - Mercy Gilbert Medical Center | Gilbert | Arizona | 85297 | — |
| 8400747 - Phoenix V.A. Health Care System | Phoenix | Arizona | 85012 | — |
| 8400772 - Mayo Clinic Arizona | Phoenix | Arizona | 85054 | — |
| 8400996 - Southern Arizona V.A. Healthcare System | Tucson | Arizona | 85723 | — |
| 8400645 - NEA Baptist Clinic | Jonesboro | Arkansas | 72401 | — |
| 8400975 - Central Arkansas Veterans Healthcare System | Little Rock | Arkansas | 72205 | — |
| 8401054 - Central Cardiology Medical Center | Bakersfield | California | 93308 | — |
| 8400379 - John Muir Health and Cardiovascular Institute | Concord | California | 94520 | — |
| 8400931 - Valley Clinical Trials | Covina | California | 91723 | — |
| 8401103 - Orange Coast Memorial Hospital | Fountain Valley | California | 92708 | — |
| 8401166 - Sharp Grossmont Hospital | La Mesa | California | 91942 | — |
| 8401192 - South Orange County Surgical Medical Group | Laguna Hills | California | 92653 | — |
| 8400596 - Long Beach Memorial Medical Center | Long Beach | California | 90806 | — |
| 8400910 - Cardiovascular Innovation and Research Center | Long Beach | California | 90813 | — |
| 8400597 - Los Alamitos Cardiovascular | Los Alamitos | California | 90720 | — |
| 8400693 - University of California Los Angeles | Los Angeles | California | 90038 | — |
| 8400717 - V.A. Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| 8400888 - Saint Jude Heritage Healthcare | Mission Viejo | California | 92691 | — |
| 8400745 - Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92663 | — |
| 8400658 - Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| 8400720 - Valley Clinical Trials | Pasadena | California | 91105 | — |
| 8400787 - Riverside Community Hospital | Riverside | California | 92501 | — |
| 8400694 - University of California San Diego Medical Center | San Diego | California | 92103 | — |
| 8400703 - San Diego Cardiac Center | San Diego | California | 92123 | — |
| 8400719 - V.A. San Diego Health Care System | San Diego | California | 92161 | — |
| 8400909 - Ventura Clinical Trials | Ventura | California | 93003 | — |
| 8400891 - John Muir Medical Center Walnu | Walnut Creek | California | 94598 | — |
| 8400893 - Interventional Cardiology Medical Group | West Hills | California | 91307 | — |
| 8400574 - Aurora Denver Cardiology Associates | Aurora | Colorado | 80012 | — |
| 8400684 - UCHealth Memorial Hospital Central - Colorado Springs | Colorado Springs | Colorado | 80909 | — |
| 8400997 - CardioVascular Institute of North Colorado Cardiology Clinic | Greeley | Colorado | 80631 | — |
| 8400670 - Medical Center of the Rockies | Loveland | Colorado | 80538 | — |
| 8400371 - Danbury Hospital | Danbury | Connecticut | 06810 | — |
| 8401134 - Christiana Hospital | Newark | Delaware | 19718 | — |
| 8400779 - MedStar Clinical Research Center | Washington D.C. | District of Columbia | 20010 | — |
| 8400688 - George Washington University Medical Center | Washington D.C. | District of Columbia | 20037 | — |
| 8400484 - Clearwater Cardiovascular and Interventional Consultants | Clearwater | Florida | 33756 | — |
| 8400544 - Cardiology Research Associates | Daytona Beach | Florida | 32117 | — |
| 8400930 - Lake Internal Medicine Assoc. | Eustis | Florida | 32726 | — |
| 8400613 - Jim Moran Heart and Vascular Center | Fort Lauderdale | Florida | 33308 | — |
| 8401010 - Integrative Research Associates Inc. | Fort Lauderdale | Florida | 33312 | — |
| 8400490 - University of Florida | Gainesville | Florida | 32610 | — |
| 8400517 - Shands Jacksonville Medical Center | Jacksonville | Florida | 32209 | — |
| 8400985 - Optimus U Corp. | Miami | Florida | 33125 | — |
| 8400543 - Cardiology Partners Research Institute | Palm Beach Gardens | Florida | 33410 | — |
| 8400542 - Cardiology Consultants | Pensacola | Florida | 32501 | — |
| 8400557 - Clearwater Cardiovascular and Interventional Consultants | Safety Harbor | Florida | 34695 | — |
| 8400686 - Intercoastal Medical Group | Sarasota | Florida | 34239 | — |
| 8400736 - Pepin Heart Institute | Tampa | Florida | 33613 | — |
| 8401011 - Cardiology Partners Research Institute | Wellington | Florida | 33449 | — |
| 8401185 - Piedmont Heart Institute | Athens | Georgia | 30606 | — |
| 8400376 - Emory University | Atlanta | Georgia | 30322-1059 | — |
| 8400918 - Augusta University | Augusta | Georgia | 30912 | — |
| 8400849 - IACT Health | Columbus | Georgia | 31904 | — |
| 8400655 - Atlanta V.A. Medical Center | Decatur | Georgia | 30033 | — |
| 8401120 - Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| 8401157 - Memorial Health University Medical Center | Savannah | Georgia | 31404 | — |
| 8400357 - Saint Luke's Boise Medical Center | Boise | Idaho | 83712 | — |
| 8400610 - Jesse Brown V.A. Medical Center | Chicago | Illinois | 60612 | — |
| 8401093 - Advanced Heart Care Group | Fairview Heights | Illinois | 62208 | — |
| 8401000 - Advocate Lutheran General Hospital | Park Ridge | Illinois | 60068 | — |
| 8400785 - OSF Multi-Specialty Group | Peoria | Illinois | 61614 | — |
| 8400361 - Midwest Cardiovascular Research | Elkhart | Indiana | 46514 | — |
| 8400961 - Indiana Heart Physicians, Inc. | Indianapolis | Indiana | 46237 | — |
| 8400989 - Indiana Heart Hospital | Indianapolis | Indiana | 46250 | — |
| 8400507 - The Saint Vincent Heart Center of Indiana | Indianapolis | Indiana | 46290 | — |
| 8400576 - IU Health Ball Memorial Hospital Physicians, Inc | Muncie | Indiana | 47303 | — |
| 8400882 - Reid Health | Richmond | Indiana | 47374 | — |
| 8400618 - McFarland Clinic, PC | Ames | Iowa | 50010 | — |
| 8400904 - Northeast Iowa Medical Education Foundation | Waterloo | Iowa | 50702 | — |
| 8400678 - The Iowa Clinic, PC | West Des Moines | Iowa | 50266 | — |
| 8400978 - Midwest Heart and Vascular | Overland Park | Kansas | 66209 | — |
| 8400661 - Norton Cardiovascular Associates | Louisville | Kentucky | 40205 | — |
| 8400368 - Cambridge Medical Trials | Alexandria | Louisiana | 71301 | — |
| 8400862 - Cardiovascular Associates Research | Covington | Louisiana | 70433 | — |
| 8401104 - Cardiovascular Institute of the South | Houma | Louisiana | 70361-4176 | — |
| 8400563 - Cardiovascular Institute of the South | Lafayette | Louisiana | 70503 | — |
| 8401127 - Tulane University Health Science Center | New Orleans | Louisiana | 70112 | — |
| 8401175 - Overton Brooks V.A. Medical Center | Shreveport | Louisiana | 71101 | — |
| 8400483 - Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| 8400812 - Maine Medical Center Bramhall Campus | Portland | Maine | 04102 | — |
| 8401142 - Anne Arundel Health System | Annapolis | Maryland | 21401 | — |
| 8401163 - Washington Adventist Hospital | Takoma Park | Maryland | 20912 | — |
| 8400998 - Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| 8400769 - Healthy Heart Cardiology | Grandville | Michigan | 49418 | — |
| 8401141 - Western Michigan University Homer Striker MD School of Medicine | Kalamazoo | Michigan | 49048 | — |
| 8400638 - Mid Michigan Regional Medical Center | Midland | Michigan | 48670 | — |
| 8401092 - Saint Joseph Mercy Oakland | Pontiac | Michigan | 48341 | — |
| 8400861 - Ascension Providence Rochester Hospital | Rochester | Michigan | 48307 | — |
| 8400372 - Covenant Medical Center | Saginaw | Michigan | 48602 | — |
| 8400667 - Michigan Cardiovascular Institute | Saginaw | Michigan | 48602 | — |
| 8401165 - Ascension Macomb-Oakland Hospital Warren Campus | Warren | Michigan | 48236 | — |
| 8400625 - Michigan Heart and Vascular Institute | Ypsilanti | Michigan | 48197 | — |
| 8400488 - Essentia Health | Duluth | Minnesota | 55805 | — |
| 8400920 - Saint Lukes Hospital | Duluth | Minnesota | 55805 | — |
| 8400364 - Minneapolis Heart Institute Foundation | Minneapolis | Minnesota | 55401 | — |
| 8400752 - Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| 8400369 - HealthEast Saint Joseph's Hospital | Saint Paul | Minnesota | 55102 | — |
| 8401168 - Jackson Heart Clinic | Jackson | Mississippi | 39216 | — |
| 8400334 - Cardiology Associates of North Mississippi | Tupelo | Mississippi | 38801 | — |
| 8401108 - University of Missouri Health System | Columbia | Missouri | 65212 | — |
| 8400648 - Saint Luke's Cardiovascular Consultants | Kansas City | Missouri | 64111 | — |
| 8400631 - North Kansas City Hospital | North Kansas City | Missouri | 64116 | — |
| 8400622 - Mercy Medical Research Institute | Springfield | Missouri | 65807 | — |
| 8400840 - Washington University | St Louis | Missouri | 63110 | — |
| 8400091 - Glacier View Cardiology | Kalispell | Montana | 59901 | — |
| 8400783 - Nebraska Heart Institute | Lincoln | Nebraska | 68526 | — |
| 8400689 - University Medical Center | Las Vegas | Nevada | 89102 | — |
| 8400545 - Advanced Heart Care LLC | Bridgewater | New Jersey | 08807 | — |
| 8400835 - Cooper University Hospital | Camden | New Jersey | 08103 | — |
| 8400836 - Our Lady of Lourdes Medical Center | Camden | New Jersey | 08103 | — |
| 8401178 - Jersey Shore University Medical Center Meridian Health | Neptune City | New Jersey | 07753 | — |
| 8401144 - Saint Michael's Medical Center | Newark | New Jersey | 07102 | — |
| 8400572 - AtlantiCare Regional Medical Center | Pomona | New Jersey | 08240 | — |
| 8401189 - Cardiovascular Associates of the Delaware Valley | Vineland | New Jersey | 08360 | — |
| 8400742 - VMG Cardiology, Westwood | Westwood | New Jersey | 07675 | — |
| 8400360 - Buffalo Heart Group | Buffalo | New York | 14215 | — |
| 8401028 - Buffalo V.A. Medical Center | Buffalo | New York | 14215 | — |
| 8400677 - Saint Joseph's Hospital Cardiac Catheterization Associates | Liverpool | New York | 13088 | — |
| 8400380 - Mount Sinai Medical Center | New York | New York | 10029 | — |
| 8401119 - Lenox Hill Hospital | New York | New York | 10075 | — |
| 8401154 - Rochester General Hospital | Rochester | New York | 14621 | — |
| 8400847 - University of Rochester Medical Center-Strong Memorial Hospital | Rochester | New York | 14642 | — |
| 8400626 - Montefiore Medical Center - Albert Einstein College of Medicine | The Bronx | New York | 10461 | — |
| 8400636 - Jacobi Medical Center | The Bronx | New York | 10461 | — |
| 8400726 - Westchester Medical Center | Valhalla | New York | 10595 | — |
| 8401027 - UNC Hospitals Heart and Vascular Center at Meadowmont | Chapel Hill | North Carolina | 27517 | — |
| 8400733 - Novant Health Heart and Vascular Institute | Charlotte | North Carolina | 28204 | — |
| 8400489 - Duke University Hospital | Durham | North Carolina | 27710 | — |
| 8400491 - Moses H. Cone Memorial Hospital | Greensboro | North Carolina | 27401-1020 | — |
| 8400366 - High Point Regional Hospital | High Point | North Carolina | 27262 | — |
| 8400916 - Southeastern Cardiology & Cardiovascular Clinic | Lumberton | North Carolina | 28358 | — |
| 8400887 - Matthews Medical Center | Matthews | North Carolina | 28105 | — |
| 8400889 - NC Heart and Vascular Research | Raleigh | North Carolina | 27607 | — |
| 8400322 - Wake Forest University Health Sciences, Dept. of Cardiovascular Medicine | Winston-Salem | North Carolina | 27157 | — |
| 8400651 - Sanford Medical Center Fargo | Fargo | North Dakota | 58122 | — |
| 8400682 - Trinity Medical Group | Minot | North Dakota | 58701 | — |
| 8400657 - Summa Health | Akron | Ohio | 44304 | — |
| 8400793 - Aultman Hospital | Canton | Ohio | 44710 | — |
| 8400858 - University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| 8401233 - Cincinnati V.A. Medical Center | Cincinnati | Ohio | 45220 | — |
| 8400966 - MetroHealth System | Cleveland | Ohio | 44109 | — |
| 8400565 - Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| 8400654 - North Ohio Research Ltd. | Elyria | Ohio | 44035 | — |
| 8400632 - North Ohio Heart Center | Sandusky | Ohio | 44870 | — |
| 8400700 - Mercy Saint Vincent Medical Center | Toledo | Ohio | 43608 | — |
| 8401164 - University of Toledo Medical Center | Toledo | Ohio | 43614 | — |
| 8400639 - Genesis Health Care System | Zanesville | Ohio | 43701 | — |
| 8400504 - Integris Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| 8400936 - South Oklahoma Heart Research | Oklahoma City | Oklahoma | 73135 | — |
| 8400664 - Oklahoma Heart Institute | Tulsa | Oklahoma | 74104 | — |
| 8401042 - Abington Medical Specialists | Abington | Pennsylvania | 19001 | — |
| 8400595 - Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| 8400608 - Holy Spirit Cardiology | Camp Hill | Pennsylvania | 17001 | — |
| 8400872 - Chambersburg Hospital | Chambersburg | Pennsylvania | 17201 | — |
| 8400577 - Doylestown Cardiology Associates | Doylestown | Pennsylvania | 18901 | — |
| 8400324 - Milton Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| 8400344 - Lancaster General Hospital | Lancaster | Pennsylvania | 17604 | — |
| 8400746 - Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| 8400718 - V.A. Pittsburgh Healthcare System | Pittsburgh | Pennsylvania | 15240 | — |
| 8400570 - Advanced Cardiology Specialists | Scranton | Pennsylvania | 18508 | — |
| 8401179 - Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| 8400794 - Geisinger Wyoming Valley | Wilkes-Barre | Pennsylvania | 18711 | — |
| 8400811 - Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| 8400591 - AnMed Health Medical Center | Anderson | South Carolina | 29621 | — |
| 8401171 - Greenville Hospital System | Greenville | South Carolina | 29605 | — |
| 8401055 - Upstate Cardiology, PA | Greenville | South Carolina | 29607 | — |
| 8400496 - Advanced Cardiology Associates | Greenwood | South Carolina | 29646 | — |
| 8400582 - Carolina Heart Specialists | Lancaster | South Carolina | 29720 | — |
| 8400320 - Black Hills Cardiovascular Research | Rapid City | South Dakota | 57701 | — |
| 8400854 - The Chattanooga Heart Institute | Chattanooga | Tennessee | 37404 | — |
| 8400500 - Tennova Health Care - Turkey Creek Medical Center | Knoxville | Tennessee | 37934 | — |
| 8400760 - V.A. Medical Center - Memphis | Memphis | Tennessee | 38104 | — |
| 8400873 - Baptist Clinical Research Institute | Memphis | Tennessee | 38120 | — |
| 8400801 - Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| 8400735 - Parkway Cardiology Associates, PC | Oak Ridge | Tennessee | 37830 | — |
| 8400551 - Cardiovascular Research of Knoxville | Powell | Tennessee | 37849 | — |
| 8400805 - PharmaTex Research | Amarillo | Texas | 79016 | — |
| 8400482 - Amarillo Heart Clinical Research Institute | Amarillo | Texas | 79106 | — |
| 8400485 - V.A. North Texas Health Care System | Dallas | Texas | 75216 | — |
| 8400911 - Brooke Army Medical Center | Fort Sam Houston | Texas | 78234-6200 | — |
| 8401231 - Revival Research Institute | McKinney | Texas | 75069 | — |
| 8400881 - North Texas Research Associates | McKinney | Texas | 75071 | — |
| 8400921 - Mission Research Institute, LLC | New Braunfels | Texas | 78130 | — |
| 8400704 - South Texas CV Consultants | San Antonio | Texas | 78201 | — |
| 8400890 - Revival Research Institute, LLC | Sherman | Texas | 75092 | — |
| 8401176 - Methodist Sugar Land Hospital | Sugar Land | Texas | 77479 | — |
| 8400521 - CAET Research | Tyler | Texas | 75701 | — |
| 8401128 - Hillcrest Family Health Center | Waco | Texas | 76710-4023 | — |
| 8400515 - Wichita Falls Heart Clinic | Wichita Falls | Texas | 76301 | — |
| 8401064 - Inova Fairfax Hospital | Falls Church | Virginia | 22042-3300 | — |
| 8400502 - Stroobants Cardiovascular Center | Lynchburg | Virginia | 24501 | — |
| 8400601 - McGuire Research Institute | Richmond | Virginia | 23249 | — |
| 8400759 - Winchester Cardiology and Vascular Medicine | Winchester | Virginia | 22601 | — |
| 8400628 - Multicare Health System | Puyallup | Washington | 98372 | — |
| 8400863 - Swedish Medical Center - Providence Campus | Seattle | Washington | 98122 | — |
| 8400503 - The Heart and Vascular Center / Holy Family Memorial | Manitowoc | Wisconsin | 54220 | — |
| 8400358 - Aspirus Research Institute | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 701 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03473223, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 13, 2025 · Synced May 12, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03473223 live on ClinicalTrials.gov.