Micronized dHACM vs. Saline in the Treatment of Osteoarthritis of the Knee
Public ClinicalTrials.gov record NCT03485157. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2B, Prospective, Double-blinded, Randomized Controlled Trial of the Micronized Dehydrated Human Amnion Chorion Membrane Injection as Compared to Saline Placebo Injection in the Treatment of Osteoarthritis of the Knee
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the safety and effectiveness of micronized dehydrated human amnion chorion membrane as compared to the 0.9% Sodium Chloride Injection, USP placebo control for the treatment of knee osteoarthritis
Study identification
- NCT ID
- NCT03485157
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 447 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 27, 2018 (Actual)
- Primary completion
- Apr 19, 2022 (Actual)
- Completion
- Apr 19, 2022 (Actual)
- Last update posted
- Dec 11, 2023
2018 – 2022
United States locations
- U.S. sites
- 17
- U.S. states
- 14
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Central Research Associates, Inc | Birmingham | Alabama | 35205 | — |
| Fiel Family and Sports Medicine | Tempe | Arizona | 85283 | — |
| Horizon Clinical Research | La Mesa | California | 91942 | — |
| UConn Health | Farmington | Connecticut | 06030 | — |
| Bone & Joint Inst. at Hartford Hospital | Hartford | Connecticut | 06106 | — |
| Gulfcoast Research Institute | Sarasota | Florida | 34232 | — |
| Paragon Sports Medicine | Atlanta | Georgia | 30327 | — |
| Hinsdale Orthopedics | Hinsdale | Illinois | 60521 | — |
| Arthritis Care Specialist of Maryland | Columbia | Maryland | 21046 | — |
| MedSport | Ann Arbor | Michigan | 48106 | — |
| Weill Cornell Medicine | New York | New York | 10065 | — |
| Wake Reseach | Durham | North Carolina | 27704 | — |
| Wake Research | Raleigh | North Carolina | 27612 | — |
| University Orthopedics Center | Altoona | Pennsylvania | 16602 | — |
| University Orthopedics Center | State College | Pennsylvania | 16801 | — |
| SAMMC | Fort Sam Houston | Texas | 78234 | — |
| Ortho Virginia | Richmond | Virginia | 23294 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03485157, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 11, 2023 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03485157 live on ClinicalTrials.gov.