ClinicalTrials.gov record
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors
ClinicalTrials.gov ID: NCT03485209
Public ClinicalTrials.gov record NCT03485209. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 6, 2026, 8:31 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Open Label Phase 2 Study of Tisotumab Vedotin for Locally Advanced or Metastatic Disease in Solid Tumors
Study identification
- NCT ID
- NCT03485209
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Seagen, a wholly owned subsidiary of Pfizer
- Industry
- Enrollment
- 350 participants
Conditions and interventions
Conditions
Interventions
- carboplatin Drug
- cisplatin Drug
- pembrolizumab Drug
- tisotumab vedotin Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 24, 2018
- Primary completion
- Mar 19, 2026
- Completion
- Mar 30, 2027
- Last update posted
- Apr 19, 2026
2018 – 2027
United States locations
- U.S. sites
- 124
- U.S. states
- 23
- U.S. cities
- 60
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCSD Medical Center - Encinitas | Encinitas | California | 92024 | — |
| UC San Diego Medical Center - La Jolla (Jacobs Medical Center / Thornton Pavilion) | La Jolla | California | 92037 | — |
| UC San Diego Moores Cancer Center | La Jolla | California | 92037 | — |
| UCSD Koman Family Outpatient Pavilion | La Jolla | California | 92037 | — |
| UC San Diego/Moores Cancer Center | La Jolla | California | 92093 | — |
| UCSD Shiley Eye Institute | La Jolla | California | 92093 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| University of California, Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| UC San Diego Medical Center- Hillcrest | San Diego | California | 92103 | — |
| UC San Diego Health - Rancho Bernardo | San Diego | California | 92127 | — |
| Stanford Cancer Center South Bay | San Jose | California | 95124 | — |
| UCSD Medical Center - Vista | Vista | California | 92081 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| Eye Center of Northern Colorado | Fort Collins | Colorado | 80525 | — |
| Cancer Care & Hematology - Fort Collins | Fort Collins | Colorado | 80528 | — |
| Eye Center of Northern Colorado | Fort Collins | Colorado | 80528 | — |
| Cancer Care & Hematology - Greeley | Greeley | Colorado | 80634 | — |
| Cancer Care & Hematology - Loveland | Loveland | Colorado | 80538 | — |
| Simlow Cancer Hospitalat Yale-New Haven | New Haven | Connecticut | 06510 | — |
| Yale-New Haven Hospital- Yale Cancer Center | New Haven | Connecticut | 06510 | — |
| C/O Thomas Ferenez.RPh,BCOP,Smilow Cancer Hospital at Yale-New Haven | New Haven | Connecticut | 06511 | — |
| Yale University | New Haven | Connecticut | 06511 | — |
| Family Focus Eye Care - Gainesville | Gainesville | Florida | 32605 | — |
| UF Health Davis Cancer Pavilion and Shands Med Plaza | Gainesville | Florida | 32608 | — |
| UF Health Shands Cancer Hospital | Gainesville | Florida | 32608 | — |
| UF Health Shands Hospital | Gainesville | Florida | 32610 | — |
| Family Focus Eye Care - Lake City | Lake City | Florida | 32025 | — |
| Moffitt Cancer Center McKinley Hospital | Tampa | Florida | 33612 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| Richard M Schulze Family Foundation Outpatient Center at McKinley Campus | Tampa | Florida | 33612 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Investigational Drug Service, Emory University Clinic | Atlanta | Georgia | 30322 | — |
| The Emory Clinic | Atlanta | Georgia | 30322 | — |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern Medical Group | Chicago | Illinois | 60611 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| UChicago Medicine - River East | Chicago | Illinois | 60611 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Northwestern Medicine Cancer Center Kishwaukee | DeKalb | Illinois | 60115 | — |
| Northwestern Medicine Kishwaukee Hospital | DeKalb | Illinois | 60115 | — |
| Northwestern University | Evanston | Illinois | 60208 | — |
| Ingalls Family Care Center (Infusion Center) | Flossmoor | Illinois | 60422 | — |
| Primary Healthcare Associates | Flossmoor | Illinois | 60422 | — |
| Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | 60134 | — |
| Northwestern Medicine Delnor Hospital | Geneva | Illinois | 60134 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Primary Healthcare Associates | Harvey | Illinois | 60426 | — |
| UChicago Medicine Ingalls Memorial | Harvey | Illinois | 60426 | — |
| University of Chicago Comprehensive Cancer Center at Silver Cross Hospital | New Lenox | Illinois | 60451 | — |
| The University of Chicago Medicine Center for Advanced Care Orland Park | Orland Park | Illinois | 60462 | — |
| Primary Healthcare Associates | Tinley Park | Illinois | 60477 | — |
| UChicago Medicine at Ingalls - Tinley Park | Tinley Park | Illinois | 60477 | — |
| Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | 60555 | — |
| Community Health Network, Inc. | Indianapolis | Indiana | 46219 | — |
| Community Health Network, Inc. | Indianapolis | Indiana | 46227 | — |
| Community Health Network, Inc. | Indianapolis | Indiana | 46250 | — |
| Community Health Network, Inc. | Indianapolis | Indiana | 46256 | — |
| The University of Kansas Cancer Center ,Investigational Drug Services | Fairway | Kansas | 66205 | — |
| The University of Kansas Clinical Research Center | Fairway | Kansas | 66205 | — |
| The University of Kansas Cancer Center | Westwood | Kansas | 66205 | — |
| Norton Cancer Institute Pharmacy | Louisville | Kentucky | 40202 | — |
| Norton Cancer Institute, Downtown | Louisville | Kentucky | 40202 | — |
| Norton Hospital | Louisville | Kentucky | 40202 | — |
| The Eye Care Institute | Louisville | Kentucky | 40206 | — |
| Norton Audubon Hospital | Louisville | Kentucky | 40217 | — |
| Norton Cancer Institute, Audubon Hospital Campus | Louisville | Kentucky | 40217 | — |
| Norton Brownsboro Hospital | Louisville | Kentucky | 40241 | — |
| Norton Cancer Institute, Brownsboro Hospital Campus | Louisville | Kentucky | 40241 | — |
| John Hopkins Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21231 | — |
| John Hopkins Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21287 | — |
| Massachusetts Eye and Ear Infirmary(MEEI) | Boston | Massachusetts | 02114 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Ophthalmic Consultants of Boston Inc (OCB) | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Karmanos Cancer Institute Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| Oncology Research, HealthPartners Institute | Saint Louis Park | Minnesota | 55426 | — |
| Park Nicollet Frauenshuh Cancer Center | Saint Louis Park | Minnesota | 55426 | — |
| Siteman Cancer Center - St. Peters | City of Saint Peters | Missouri | 63376 | — |
| Siteman Cancer Center - West County | Creve Coeur | Missouri | 63141 | — |
| Siteman Cancer Center - North County | Florissant | Missouri | 63031 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Washington University - Investigational Drug Service Pharmacy | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Siteman Cancer Center - South County | St Louis | Missouri | 63129 | — |
| MSK Basking Ridge. | Basking Ridge | New Jersey | 07920 | — |
| MSK Monmouth | Middletown | New Jersey | 07748 | — |
| MSK Bergen | Montvale | New Jersey | 07645 | — |
| MSK Commack. | Commack | New York | 11725 | — |
| MSK Westchester. | Harrison | New York | 10604 | — |
| Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street). | New York | New York | 10021 | — |
| MSK Nassau. | Uniondale | New York | 11553 | — |
| North Carolina Basnight Cancer Hospital Infusion Pharmacy | Chapel Hill | North Carolina | 27514 | — |
| UNC Hospitals, The University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27514 | — |
| The University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Duke Cancer Center | Durham | North Carolina | 27710 | — |
| Investigational Chemotherapy Service | Durham | North Carolina | 27710 | — |
| Duke Raleigh Hospital | Raleigh | North Carolina | 27609 | — |
| Atrium Health Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| Atrium Health Wake forest Baptist | Winston-Salem | North Carolina | 27157 | — |
| OHSU Knight Cancer Institute, Beaverton | Beaverton | Oregon | 97006 | — |
| OHSU Knight Cancer Institute, Gresham | Gresham | Oregon | 97030 | — |
| OHSU Knight Cancer Institute, Northwest Portland | Portland | Oregon | 97210 | — |
| OHSU Knight Cancer Institute, East Portland | Portland | Oregon | 97216 | — |
| OHSU Center for Health and Healing 2 | Portland | Oregon | 97239 | — |
| OHSU Center for Health and Healing | Portland | Oregon | 97239 | — |
| Oregon Health and Science University Research Pharmacy Services | Portland | Oregon | 97239 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| OHSU Knight Cancer Institute, Tualatin | Tualatin | Oregon | 97062 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | — |
| Renovatio Clinical. | The Woodlands | Texas | 77380 | — |
| Cancer Center IDS Pharmacy | Charlottesville | Virginia | 22903 | — |
| University of Virginia Comprehensive Cancer Center | Charlottesville | Virginia | 22903 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| UVA Health System; Attention: GI Team | Charlottesville | Virginia | 22908 | — |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03485209, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03485209 live on ClinicalTrials.gov.