Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease
Public ClinicalTrials.gov record NCT03486938. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of AGB101on Slowing Progression of Mild Cognitive Impairment Due to Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of the study is to evaluate the efficacy of AGB101 on slowing cognitive and functional impairment as measured by changes in the Clinical Dementia Rating-Sum of Boxes (CDR-SB) score as compared with placebo in participants with mild cognitive impairment due to Alzheimer's Disease (MCI due to AD) also known as prodromal AD. Participants will be randomized to receive placebo or AGB101 (220 mg), once daily for 78 weeks. Secondary objectives are to assess the effect of AGB101 compared with placebo on clinical progression as measured by Mini-Mental State Examination (MMSE) and Functional Activities Questionnaire (FAQ).
Study identification
- NCT ID
- NCT03486938
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 164 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 55 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 12, 2018
- Primary completion
- Nov 1, 2022
- Completion
- Nov 1, 2022
- Last update posted
- May 16, 2024
2018 – 2022
United States locations
- U.S. sites
- 23
- U.S. states
- 12
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | — |
| Senior Clinical Trials, Inc. | Laguna Hills | California | 92653 | — |
| Excell Research Inc | Oceanside | California | 92056 | — |
| The Mile High Research Center | Denver | Colorado | 80218 | — |
| Boynton Beach Medical Research Institite | Boynton Beach | Florida | 33437 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| MD Clinical | Hallandale | Florida | 33009 | — |
| Miami Jewish Health | Miami | Florida | 33137 | — |
| Bioclinica Research | Orlando | Florida | 32806 | — |
| IMIC Research | Palmetto Bay | Florida | 33157 | — |
| The Roskamp Institute, Inc | Sarasota | Florida | 34243 | — |
| Brain Matters Research | Stuart | Florida | 34997 | — |
| NeuroStudies.net, LLC | Decatur | Georgia | 30033 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21205 | — |
| Memory Center/Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| The NeuroCognitive Institute | Mount Arlington | New Jersey | 07856 | — |
| Global Medical Institutes LLC; Princeton Medical Institute | Princeton | New Jersey | 08540 | — |
| Neurology Specialist of Monmouth County, PA | West Long Branch | New Jersey | 07764 | — |
| Neurological Associates of Albany PC | Albany | New York | 12208 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10312 | — |
| Clinical Biotechnology Research Institute at RSFH | Charleston | South Carolina | 29401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03486938, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 16, 2024 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03486938 live on ClinicalTrials.gov.