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Completed Phase 1 Interventional

MEDI2228 in Subjects With Relapsed/Refractory Multiple Myeloma

ClinicalTrials.gov ID: NCT03489525

Public ClinicalTrials.gov record NCT03489525. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 4, 2026, 4:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Open-label Study to Evaluate the Safety, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of MEDI2228 in Subjects With Relapsed/Refractory Multiple Myeloma

Study identification

NCT ID
NCT03489525
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
MedImmune LLC
Industry
Enrollment
107 participants

Conditions and interventions

Interventions

  • Dose Escalation, MEDI2228, ADC (antibody drug conjugate) Biological
  • Dose Expansion, MEDI2228, ADC (antibody drug conjugate) Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 101 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 7, 2018
Primary completion
Mar 20, 2022
Completion
Mar 20, 2022
Last update posted
Mar 27, 2022

2018 – 2022

United States locations

U.S. sites
8
U.S. states
7
U.S. cities
7
Facility City State ZIP Site status
Research Site Phoenix Arizona 85054
Research Site Jacksonville Florida 32224
Research Site Boston Massachusetts 02114
Research Site Boston Massachusetts 02215
Research Site Detroit Michigan 48201
Research Site Rochester Minnesota 55905
Research Site Charlotte North Carolina 28204
Research Site Fairfax Virginia 22031

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03489525, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 27, 2022 · Synced May 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03489525 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →