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Terminated Phase 3 Interventional Results available

An Open-Label Crenezumab Study in Participants With Alzheimer's Disease

ClinicalTrials.gov ID: NCT03491150

Public ClinicalTrials.gov record NCT03491150. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 13, 2026, 7:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Open-Label, Long-Term Extension Of Phase III Studies (BN29552/BN29553) Of Crenezumab In Patients With Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

In the BN40031 OLE study, a dose of crenezumab of 60 mg/kg intravenous (IV) every 4 weeks (Q4W) will be offered to all participants who complete Study BN29552 or BN29553 and who meet eligibility criteria in order to evaluate safety in participants on long-term crenezumab treatment and to investigate the effect of crenezumab on the underlying disease process and disease course as an exploratory efficacy objective.

Study identification

NCT ID
NCT03491150
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
149 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
Not listed
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 10, 2018
Primary completion
May 30, 2019
Completion
May 30, 2019
Last update posted
Jul 12, 2020

2018 – 2019

United States locations

U.S. sites
32
U.S. states
15
U.S. cities
31
Facility City State ZIP Site status
Shankle Clinic Newport Beach California 92663
Anderson Clinical Research, Inc. Redlands California 92374
University of California, Davis; Alzheimers Disease Center, Department of Neurology Sacramento California 95817
UCSF - Memory and Aging Center San Francisco California 94158
Neurological Research Inst Santa Monica California 90404
Associated Neurologists PC - Danbury Danbury Connecticut 06810
Institute for Neurodegenerative Disorders New Haven Connecticut 06510
Yale University School Of Medicine New Haven Connecticut 06510
Research Center for Clinical Studies, Inc. Norwalk Connecticut 06851
Bradenton Research Center Bradenton Florida 34205
Brain Matters Research, Inc. Delray Beach Florida 33445
Alzheimer's Research and Treatment Center Lake Worth Florida 33414
Renstar Medical Research Ocala Florida 34470
Bioclinica Research Orlando Florida 32806
Progressive Medical Research Port Orange Florida 32127
Stedman Clinical Trials, LLC Tampa Florida 33613
NeuroStudies.net, LLC Decatur Georgia 30033
Alexian Brothers Neurosci Inst Elk Grove Village Illinois 60007
Southern Illinois University, School of Medicine Springfield Illinois 62702
MidAmerica Neuroscience Institute Prairie Village Kansas 66206
MMP Neurology Scarborough Maine 04074
Precise Research Centers Flowood Mississippi 39232
The Cognitive and Research Center of New Jersey Springfield New Jersey 07081
Advanced Memory Research Institute of NJ Toms River New Jersey 08755
Behavioral Health Research Charlotte North Carolina 28211
Guilford Neurologic Associates Greensboro North Carolina 27401
Oklahoma Clinical Research Oklahoma City Oklahoma 73112
Summit Research Network Inc. Portland Oregon 97210
Abington Neurological Associates Willow Grove Pennsylvania 19090
Senior Adults Specialty Research Austin Texas 78757
Sentara Medical Group Norfolk Virginia 23507
National Clinical Research Inc.-Richmond Richmond Virginia 23294

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 34 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03491150, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 12, 2020 · Synced Sep 13, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03491150 live on ClinicalTrials.gov.

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