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Completed Phase 1 Interventional

To Assess the Patients' Ability to Self-Administer Fasinumab

ClinicalTrials.gov ID: NCT03491904

Public ClinicalTrials.gov record NCT03491904. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 2:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Multicenter, Randomized, Open-Label, Parallel-Group, Multi-Dose Study in Patients With Moderate-to-Severe Pain Due to Osteoarthritis of the Knee or Hip to Assess the Patients' Ability to Self-Administer Fasinumab Using an Auto-Injector and to Characterize the Pharmacokinetics of Fasinumab Using Two Different Presentations

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective is to demonstrate that the auto-injector(AI) is suitable to be used to administer fasinumab at home by patients or their caregivers, as measured by collecting 12 weeks of actual-use data on the technical performance of the device. The secondary objectives of the study are: * To evaluate the successful injection of fasinumab by patients or their caregivers using the AI in an unsupervised setting * To evaluate patient/caregiver satisfaction with the AI for fasinumab injection in an unsupervised setting * To evaluate exposure in serum for fasinumab administered by patients or their caregivers using an AI in an unsupervised setting, or fasinumab administered by study staff using a PFS that has been used in the phase 3 program * To characterize the safety, tolerability, and immunogenicity of fasinumab administered by patients or their caregivers using an AI in an unsupervised setting, or fasinumab administered by study staff using a PFS that has been used in the phase 3 program

Study identification

NCT ID
NCT03491904
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Regeneron Pharmaceuticals
Industry
Enrollment
100 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 22, 2019
Primary completion
Jan 14, 2020
Completion
Dec 14, 2020
Last update posted
Mar 2, 2021

2019 – 2020

United States locations

U.S. sites
23
U.S. states
13
U.S. cities
20
Facility City State ZIP Site status
Regeneron Research Facility Gilbert Arizona 85297
Regeneron Research Facility Glendale Arizona 85307
Regeneron Research Facility Los Angeles California 90029
Regeneron Research Facility Wheat Ridge Colorado 80033
Regeneron Research Facility Ocala Florida 34471
Regeneron Research Facility Orlando Florida 32822
Regeneron Research Facility Pinellas Park Florida 33781
Regeneron Research Facility Port Orange Florida 32127
Regeneron Research Facility Atlanta Georgia 30342
Regeneron Research Facility West Des Moines Iowa 50265
Regeneron Research Facility Wichita Kansas 67205
Regeneron Research Facility Lexington Kentucky 40503
Regeneron Research Facility Lexington Kentucky 40504
Regeneron Research Facility Jamaica New York 11432
Regeneron Research Facility Statesville North Carolina 28625
Regeneron Research Facility Wilmington North Carolina 28401
Regeneron Research Facility Oklahoma City Oklahoma 73114
Regeneron Research Facility Bristol Tennessee 37620
Regeneron Research Facility Knoxville Tennessee 37938
Regeneron Research Facility Dallas Texas 75231
Regeneron Research Facility Houston Texas 77024
Regeneron Research Facility Houston Texas 77089
Regeneron Research Facility Houston Texas 77804

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03491904, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 2, 2021 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03491904 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →