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Completed Phase 3 Interventional Results available

Study of Sparsentan in Patients With Primary Focal Segmental Glomerulosclerosis (FSGS)

ClinicalTrials.gov ID: NCT03493685

Public ClinicalTrials.gov record NCT03493685. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 11:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Multicenter, Double-blind, Parallel, Active-control Study of the Effects of Sparsentan, a Dual Endothelin Receptor and Angiotensin Receptor Blocker, on Renal Outcomes in Patients With Primary FSGS

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To determine the long-term nephroprotective potential of treatment with sparsentan as compared to an angiotensin receptor blocker in patients with primary and genetic focal segmental glomerulosclerosis (FSGS).

Study identification

NCT ID
NCT03493685
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Travere Therapeutics, Inc.
Industry
Enrollment
371 participants

Conditions and interventions

Eligibility (public fields only)

Age range
8 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 17, 2018 (Actual)
Primary completion
Mar 20, 2023 (Actual)
Completion
Mar 19, 2026 (Actual)
Last update posted
Apr 17, 2026

2018 – 2026

United States locations

U.S. sites
87
U.S. states
33
U.S. cities
76
Facility City State ZIP Site status
Travere Investigational Site Mesa Arizona 85210 —
Travere Investigational Site Phoenix Arizona 85027 —
Travere Investigational Site Los Angeles California 90048 —
Travere Investigational Site Northridge California 91324 —
Travere Investigational Site Palo Alto California 94304 —
Travere Investigational Site San Diego California 92103 —
Travere Investigational Site San Dimas California 91773 —
Travere Investigational Site San Francisco California 94118 —
Travere Investigational Site Torrance California 90502 —
Travere Investigational Site Victorville California 92395 —
Travere Investigational Site Denver Colorado 80205 —
Travere Investigational Site Denver Colorado 80230 —
Travere Investigational Site Middlebury Connecticut 06762 —
Travere Investigational Site Wilmington Delaware 19803 —
Travere Investigational Site Washington D.C. District of Columbia 20010 —
Travere Investigational Site Coral Springs Florida 33071 —
Travere Investigational Site Fort Lauderdale Florida 33308 —
Travere Investigational Site Gainesville Florida 32610 —
Travere Investigational Site Miami Florida 33126 —
Travere Investigational Site Miami Florida 33136 —
Travere Investigational Site Miami Florida 33155 —
Travere Investigational Site Ocala Florida 34471 —
Travere Investigational Site Orlando Florida 32827 —
Travere Investigational Site Port Charlotte Florida 33952 —
Travere Investigational Site Temple Terrace Florida 33637 —
Travere Investigational Site Winter Park Florida 32789 —
Travere Investigational Site Lawrenceville Georgia 30046 —
Travere Investigational Site Nampa Idaho 86387 —
Travere Investigational Site Chicago Illinois 60611 —
Travere Investigational Site Hinsdale Illinois 60521 —
Travere Investigational Site Kansas City Kansas 66160 —
Travere Investigational Site Wichita Kansas 67214 —
Travere Investigational Site Louisville Kentucky 40202 —
Travere Investigational Site Monroe Louisiana 71201 —
Travere Investigational Site New Orleans Louisiana 70121 —
Travere Investigational Site Shreveport Louisiana 71101 —
Travere Investigational Site Boston Massachusetts 02111 —
Travere Investigational Site Springfield Massachusetts 01107 —
Travere Investigational Site Ann Arbor Michigan 48109 —
Travere Investigational Site Detroit Michigan 48202 —
Travere Investigational Site Minneapolis Minnesota 55404 —
Travere Investigational Site Minneapolis Minnesota 55455 —
Travere Investigational Site Rochester Minnesota 55902 —
Travere Investigational Site Kansas City Missouri 64108 —
Travere Investigational Site Kansas City Missouri 64111 —
Travere Investigational Site Las Vegas Nevada 89129 —
Travere Investigational Site Reno Nevada 89511 —
Travere Investigational Site Hackensack New Jersey 07601 —
Travere Investigational Site Fresh Meadows New York 11365 —
Travere Investigational Site New Hyde Park New York 11040 —
Travere Investigational Site New York New York 10016 —
Travere Investigational Site New York New York 10029 —
Travere Investigational Site New York New York 10032 —
Travere Investigational Site The Bronx New York 10467 —
Travere Investigational Site Chapel Hill North Carolina 27514 —
Travere Investigational Site Durham North Carolina 27710 —
Travere Investigational Site Raleigh North Carolina 27609 —
Travere Investigational Site Winston-Salem North Carolina 27103 —
Travere Investigational Site Cleveland Ohio 44195 —
Travere Investigational Site Columbus Ohio 43210 —
Travere Investigational Site Oklahoma City Oklahoma 73104 —
Travere Investigational Site Roseburg Oregon 97471 —
Travere Investigational Site Bethlehem Pennsylvania 18017 —
Travere Investigational Site Camp Hill Pennsylvania 17011 —
Travere Investigational Site Philadelphia Pennsylvania 19104 —
Travere Investigational Site Pittsburgh Pennsylvania 15224 —
Travere Investigational Site Upland Pennsylvania 19013 —
Travere Investigational Site Columbia South Carolina 29203 —
Travere Investigational Site Memphis Tennessee 38103 —
Travere Investigational Site Corpus Christi Texas 78412 —
Travere Investigational Site Dallas Texas 75231 —
Travere Investigational Site Dallas Texas 75235 —
Travere Investigational Site Dallas Texas 75246 —
Travere Investigational Site El Paso Texas 79902 —
Travere Investigational Site Fort Worth Texas 76104 —
Travere Investigational Site Houston Texas 77030 —
Travere Investigational Site Houston Texas 77054 —
Travere Investigational Site Lewisville Texas 75057 —
Travere Investigational Site Sherman Texas 75090 —
Travere Investigational Site Salt Lake City Utah 84112 —
Travere Investigational Site Salt Lake City Utah 84115 —
Travere Investigational Site St. George Utah 84790 —
Travere Investigational Site Hampton Virginia 23666 —
Travere Investigational Site Spokane Washington 99204 —
Travere Investigational Site Morgantown West Virginia 26506 —
Travere Investigational Site Marshfield Wisconsin 54449 —
Travere Investigational Site Wauwatosa Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 139 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03493685, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 17, 2026 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03493685 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →