Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial
Public ClinicalTrials.gov record NCT03496883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Recombinant Factor VIIa (rFVIIa) for Acute Hemorrhagic Stroke Administered at Earliest Time (FASTEST) Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of the rFVIIa for Acute Hemorrhagic Stroke Administered at Earliest Time (FASTEST) Trial is to establish the first treatment for acute spontaneous intracerebral hemorrhage (ICH) within a time window and subgroup of patients that is most likely to benefit. The central hypothesis is that rFVIIa, administered within 120 minutes from stroke onset with an identified subgroup of patients most likely to benefit, will improve outcomes at 180 days as measured by the Modified Rankin Score (mRS) and decrease ongoing bleeding as compared to standard therapy.
Study identification
- NCT ID
- NCT03496883
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 860 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 3, 2021 (Actual)
- Primary completion
- Jan 1, 2028 (Estimated)
- Completion
- Jan 1, 2028 (Estimated)
- Last update posted
- Jan 21, 2026
2021 – 2028
United States locations
- U.S. sites
- 51
- U.S. states
- 21
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Hospital | Birmingham | Alabama | 35233 | — |
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Kaiser Permanente Baldwin Park Medical Center | Baldwin Park | California | 91706 | — |
| Mills Peninsula Medical Center | Burlingame | California | 94010 | — |
| Kaiser Permanente Downey Medical Center | Downey | California | 90242 | — |
| Kaiser Permanente Fontana Medical Center | Fontana | California | 92335 | — |
| Kaiser Permanente South Bay Medical Center | Harbor City | California | 90710 | — |
| UCSD Health La Jolla | La Jolla | California | 92037 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Kaiser Permanente West Los Angeles Medical Center | Los Angeles | California | 90034 | — |
| Ronald Reagan UCLA Medical Center | Los Angeles | California | 90095 | — |
| UC Irvine Medical Center, | Orange | California | 92868 | — |
| Kaiser Permanente Riverside Medical Center | Riverside | California | 92505 | — |
| UC Davis Medical Center | Sacramento | California | 95817 | — |
| UCSD Medical Center - Hillcrest Hospital | San Diego | California | 92103 | — |
| San Francisco General Hospital | San Francisco | California | 94110 | — |
| UF Health Shands Hospital | Gainesville | Florida | 32608 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Grady Memorial Hospital | Atlanta | Georgia | 30303 | — |
| WellStar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| The Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Central DuPage Hospital | Winfield | Illinois | 60190 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01605 | — |
| Henry Ford Hospital | Detroit | Michigan | 48208 | — |
| M Health Fairview Ridges Hospital, | Burnsville | Minnesota | 55337 | — |
| M Health Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| M Health Fairview St. John's Hospital | Maplewood | Minnesota | 55109 | — |
| M Health Fairview University of Minnesota Medical Center Hospital, | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic Saint Marys Campus | Rochester | Minnesota | 55902 | — |
| Barnes Jewish Hospital | St Louis | Missouri | 63110 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Mount Sinai West | New York | New York | 10019 | — |
| The Mount Sinai Hospital | New York | New York | 10029 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| Wake Forest Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45229 | — |
| OSU Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| Toledo Hospital | Toledo | Ohio | 43606 | — |
| St. John Medical Center | Tulsa | Oklahoma | 74104 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Medical University of South Carolina University Hospital | Charleston | South Carolina | 29425 | — |
| Prisma Health Greenville Memorial Hospital | Greenville | South Carolina | 29605 | — |
| Memorial Hermann Memorial City Medical Center | Houston | Texas | 77024 | — |
| Memorial Hermann-Texas Medical Center | Houston | Texas | 77030 | — |
| University of Utah Healthcare | Salt Lake City | Utah | 84132 | — |
| VCU Medical Center | Richmond | Virginia | 23219 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03496883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 21, 2026 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03496883 live on ClinicalTrials.gov.