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Completed Phase 4 Interventional Results available

EXPEDITE: A Study of Remodulin Induction Followed by Orenitram Optimization to Treat Pulmonary Arterial Hypertension

ClinicalTrials.gov ID: NCT03497689

Public ClinicalTrials.gov record NCT03497689. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 10:53 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

EXPEDITE: A 16-Week, Multicenter, Open-label Study of Remodulin Induction Followed by Orenitram Optimization in Subjects With Pulmonary Arterial Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This was a multicenter, open-label study to evaluate the dose of Orenitram® (treprostinil) Extended Release Tablets achieved at 16 weeks after a short-term course of Remodulin® (treprostinil) Injection in subjects with pulmonary arterial hypertension (PAH).

Study identification

NCT ID
NCT03497689
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
United Therapeutics
Industry
Enrollment
36 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 30, 2019
Primary completion
May 10, 2022
Completion
May 10, 2022
Last update posted
Aug 6, 2023

2019 – 2022

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
University of California San Francisco - Fresno Fresno California 93701
Harbor-UCLA Medical Center Torrance California 90502
Florida Hospital Orlando Florida 32803
Piedmont Healthcare Pulmonary and Critical Care Research Austell Georgia 30106
St. Vincent Medical Group Indianapolis Indiana 46260
University of Nebraska Medical Center Omaha Nebraska 68198
University of New Mexico Health Sciences Center Albuquerque New Mexico 87131
University of Cincinnati Health Cincinnati Ohio 45267
The Ohio State University Wexner Medical Center Columbus Ohio 43210
Integris Baptist Medical Center Oklahoma City Oklahoma 73112
UPMC Presbytarian Hospital Pittsburgh Pennsylvania 15213

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03497689, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 6, 2023 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03497689 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →