ClinicalTrials.gov record
Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer
ClinicalTrials.gov ID: NCT03499353
Public ClinicalTrials.gov record NCT03499353. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2, NON RANDOMIZED, OPEN LABEL, SINGLE ARM, MULTI CENTER STUDY OF TALAZOPARIB FOR NEOADJUVANT TREATMENT OF GERMLINE BRCA1/2 MUTATION PATIENTS WITH EARLY HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 NEGATIVE BREAST CANCER
Study identification
- NCT ID
- NCT03499353
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 61 participants
Conditions and interventions
Conditions
Interventions
- TALAZOPARIB Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 26, 2018
- Primary completion
- Sep 22, 2020
- Completion
- Sep 22, 2020
- Last update posted
- Nov 8, 2021
2018 – 2020
United States locations
- U.S. sites
- 97
- U.S. states
- 18
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Gateway Medical Center | Gilbert | Arizona | 85234 | — |
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | — |
| Highlands Oncology Group | Fayetteville | Arkansas | 72703 | — |
| Highlands Oncology Group | Rogers | Arkansas | 72758 | — |
| PMK Medical Group Inc., dba Ventura County Hematology Oncology Specialists | Camarillo | California | 93010 | — |
| City of Hope (City of Hope National Medical Center, City of Hope Medical Center) | Duarte | California | 91010 | — |
| City of Hope Investigational Drug Services (IDS) | Duarte | California | 91010 | — |
| The Oncology Institute of Hope & Innovation | Glendale | California | 91204 | — |
| Glendale Adventist Medical Center | Glendale | California | 91206 | — |
| The Oncology Institute of Hope & Innovation | Long Beach | California | 90805 | — |
| UC Irvine Health | Orange | California | 92868-3201 | — |
| UC Irvine Medical Center | Orange | California | 92868-3201 | — |
| PMK Medical Group Inc., dba Ventura County Hematology Oncology Specialists | Oxnard | California | 93030 | — |
| Emad Ibrahim, MD, INC. | Redlands | California | 92373 | — |
| The Oncology Institute of Hope & Innovation | Santa Ana | California | 92705 | — |
| Stanford Cancer Institute | Stanford | California | 94305 | — |
| Stanford Hospital and Clinics | Stanford | California | 94305 | — |
| Stanford Women's Cancer Center | Stanford | California | 94305 | — |
| PMK Medical Group Inc., dba Ventura County Hematology Oncology Specialists | Ventura | California | 93003 | — |
| The Oncology Institute of Hope & Innovation | West Covina | California | 91790 | — |
| The Oncology Institute of Hope & Innovation | Whittier | California | 90602 | — |
| ICRI | Whittier | California | 90603 | — |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | — |
| Rocky Mountain Cancer Centers | Boulder | Colorado | 80303 | — |
| Rocky Mountain Cancer Centers | Colorado Springs | Colorado | 80907 | — |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80218 | — |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80220 | — |
| Rocky Mountain Cancer Centers | Englewood | Colorado | 80113 | — |
| Rocky Mountain Cancer Centers | Lakewood | Colorado | 80228 | — |
| Rocky Mountain Cancer Centers | Littleton | Colorado | 80120-4413 | — |
| Rocky Mountain Cancer Centers | Lone Tree | Colorado | 80124 | — |
| Rocky Mountain Cancer Centers | Longmont | Colorado | 80501 | — |
| Rocky Mountain Cancer Centers | Parker | Colorado | 80138 | — |
| Rocky Mountain Cancer Centers | Pueblo | Colorado | 81008 | — |
| Rocky Mountain Cancer Centers | Thornton | Colorado | 80260 | — |
| Innovative Medical Research of South Florida, Inc | Aventura | Florida | 33180 | — |
| Grady Health System | Atlanta | Georgia | 30303 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| The Emory Clinic | Atlanta | Georgia | 30322 | — |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Emory Saint Joseph's Hospital | Atlanta | Georgia | 30342 | — |
| Rush University Medical Center, Professional Office Building Infusion Pharmacy | Chicago | Illinois | 60612 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Rush Oak Park Hospital | Oak Park | Illinois | 60304 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39213 | — |
| Summit Medical Group | Berkeley Heights | New Jersey | 07922 | — |
| Summit Medical Group PA | Florham Park | New Jersey | 07932 | — |
| St. Luke's Hospital - Warren Campus | Phillipsburg | New Jersey | 08865 | — |
| St. Luke's Warren Physician Group | Phillipsburg | New Jersey | 08865 | — |
| Northwest Cancer Specialists, P.C. | Portland | Oregon | 97213-2982 | — |
| Northwest Cancer Specialists, P.C. | Portland | Oregon | 97227 | — |
| Northwest Cancer Specialists, P.C. | Tigard | Oregon | 97223 | — |
| St. Luke's Hematology Oncology Specialists | Allentown | Pennsylvania | 18104 | — |
| St. Luke's Hospital - Allentown Campus | Allentown | Pennsylvania | 18104 | — |
| St. Luke's Hematology Oncology Specialists | Bethlehem | Pennsylvania | 18015 | — |
| St. Luke's Hospital - Bethlehem Campus | Bethlehem | Pennsylvania | 18015 | — |
| St. Luke's Hospital - Miners Campus | Coaldale | Pennsylvania | 18218 | — |
| St Luke's Hospital - Anderson Campus | Easton | Pennsylvania | 18045 | — |
| St. Luke's Hospital - Anderson Campus | Easton | Pennsylvania | 18045 | — |
| UPMC Hillman Cancer Center Mountainview Arnold Palmer Pavilion | Greensburg | Pennsylvania | 15601 | — |
| UPMC Cancer Centers East Oxford Drive | Monroeville | Pennsylvania | 15146 | — |
| Magee-Womens Hospital of UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC Hillman Cancer Center North Hills at Passavant | Pittsburgh | Pennsylvania | 15237 | — |
| UPMC Hillman Cancer Center UPMC Passavant | Pittsburgh | Pennsylvania | 15237 | — |
| St. Luke's Hospital - Quakertown Campus | Quakertown | Pennsylvania | 18951 | — |
| St. Luke's Hospital - Monroe Campus | Stroudsburg | Pennsylvania | 18360 | — |
| UPMC Hillman Cancer Center Uniontown | Uniontown | Pennsylvania | 15401 | — |
| UPMC Hillman Cancer Center Washington | Washington | Pennsylvania | 15301 | — |
| Charleston Hematology Oncology Associates, PA | Charleston | South Carolina | 29414 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Avera Specialty Hospital | Sioux Falls | South Dakota | 57108 | — |
| Brig Center for Cancer Care and Survivorship | Knoxville | Tennessee | 37909 | — |
| Baptist Cancer Center | Memphis | Tennessee | 38120 | — |
| Texas Oncology - Allen | Allen | Texas | 75013 | — |
| Texas Oncology - Austin Midtown | Austin | Texas | 78705 | — |
| Texas Oncology-Austin Central | Austin | Texas | 78731 | — |
| Texas Oncology - South Austin | Austin | Texas | 78745 | — |
| Texas Oncology-Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Texas Oncology-Denton South | Denton | Texas | 76210 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| U.T. MD Anderson Cancer Center, Investigational Pharmacy Services - Unit 376 | Houston | Texas | 77030 | — |
| U.T. MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| US Oncology Investigational Products Center (IPC) | Irving | Texas | 75063 | — |
| Texas Oncology - McKinney | McKinney | Texas | 75071 | — |
| Texas Oncology - Round Rock | Round Rock | Texas | 78681 | — |
| Virginia Oncology Associates | Chesapeake | Virginia | 23320 | — |
| Virginia Oncology Associates | Hampton | Virginia | 23666 | — |
| Virginia Oncology Associates | Newport News | Virginia | 23606 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Virginia Oncology Associates | Virginia Beach | Virginia | 23456 | — |
| Northwest Cancer Specialists, P.C. | Vancouver | Washington | 98683 | — |
| Northwest Cancer Specialists, P.C. | Vancouver | Washington | 98684 | — |
| University of Wisconsin Clinical Science Center | Madison | Wisconsin | 53792 | — |
| UW Health University Hospital - Pharmaceutical Research Center | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03499353, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 8, 2021 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03499353 live on ClinicalTrials.gov.