Vitamin C, Thiamine, and Steroids in Sepsis
Public ClinicalTrials.gov record NCT03509350. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-center, Randomized, Placebo-controlled, Double-blind, Adaptive Clinical Trial of Vitamin C, Thiamine and Steroids as Combination Therapy in Patients With Sepsis.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The VItamin C, Thiamine And Steroids in Sepsis (VICTAS) Study is a double-blind, placebo-controlled, adaptive randomized clinical trial designed to investigate the efficacy of the combined use of vitamin C, thiamine and corticosteroids versus indistinguishable placebos for patients with sepsis. The objective of this study is to demonstrate the efficacy of combination therapy using vitamin C, thiamine and corticosteroids in reducing mortality and improving organ function in critically ill patients with sepsis.
Study identification
- NCT ID
- NCT03509350
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 501 participants
Conditions and interventions
Conditions
Interventions
- Vitamin C Drug
- Thiamine Drug
- Hydrocortisone Drug
- Vitamin C Placebo Drug
- Thiamine Placebo Drug
- Hydrocortisone Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 22, 2018 (Actual)
- Primary completion
- Aug 22, 2019 (Actual)
- Completion
- Jan 29, 2020 (Actual)
- Last update posted
- Apr 13, 2021
2018 – 2020
United States locations
- U.S. sites
- 43
- U.S. states
- 23
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Maricopa Integrated Health System | Phoenix | Arizona | 80045 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| David Geffen School of Medicine at UCLA | Los Angeles | California | 30322 | — |
| Stanford University | Stanford | California | 21201 | — |
| University of Colorado Denver | Denver | Colorado | 19140 | — |
| Denver Health | Denver | Colorado | 80204 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 94304 | — |
| Christiana Care | Newark | Delaware | 19718 | — |
| Medstar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| University of Florida Jacksonville | Jacksonville | Florida | 32209 | — |
| Piedmont Healthcare | Atlanta | Georgia | 30078 | — |
| Grady Memorial Hospital | Atlanta | Georgia | 30303 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Emory Saint Joseph's Hospital | Atlanta | Georgia | 30342 | — |
| Lousiana State University | New Orleans | Louisiana | 70112 | — |
| Johns Hopkins Bayview | Baltimore | Maryland | 21224 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| University of Maryland School of Medicine | Baltimore | Maryland | 55415 | — |
| Baystate Health | Springfield | Massachusetts | 01199 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 27710 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 48202 | — |
| Mayo Clinic | Rochester | Minnesota | 55902 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Montefiore Medical Center Weiler | The Bronx | New York | 10461 | — |
| Montefiore Medical Center Moses | The Bronx | New York | 10467 | — |
| Duke University | Durham | North Carolina | 90024 | — |
| Wake Forest University | Winston-Salem | North Carolina | 43210 | — |
| University of Cincinnati Physicians Company | Cincinnati | Ohio | 23114 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Ohio State University Wexner Medical Center | Columbus | Ohio | 45241 | — |
| Oregon Health Sciences University | Portland | Oregon | 27157 | — |
| University of Pennsylvania Health System Hospital | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 21224 | — |
| Temple University | Philadelphia | Pennsylvania | 29425 | — |
| Medical University of South Carolina | Charleston | South Carolina | 19107 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Intermountain Medical Center | Murray | Utah | 84157 | — |
| University of Utah | Salt Lake City | Utah | 37235 | — |
| Sentara Healthcare | Norfolk | Virginia | 23507 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23284 | — |
| Bon Secours | Richmond | Virginia | 85008 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03509350, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2021 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03509350 live on ClinicalTrials.gov.