The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
Public ClinicalTrials.gov record NCT03509961. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Pilot Trial to Estimate Survival After a Non-total Body Irradiation (TBI) Based Conditioning Regimen in Patients Diagnosed With B-acute Lymphoblastic Leukemia (ALL) Who Are Pre-allogeneic Hematopoietic Cell Transplantation (HCT) Next-generation-sequence (NGS) Minimal Residual Disease (MRD) Negative
Study identification
- NCT ID
- NCT03509961
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Pediatric Transplantation & Cellular Therapy Consortium
- Other
- Enrollment
- 95 participants
Conditions and interventions
Conditions
Interventions
- Myeloablative allogeneic HCT with a non-TBI conditioning regimen Drug
- NGS-MRD Diagnostic Test
Drug · Diagnostic Test
Eligibility (public fields only)
- Age range
- 1 Year to 25 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 28, 2018
- Primary completion
- Jun 30, 2025
- Completion
- Jun 30, 2026
- Last update posted
- May 3, 2025
2018 – 2026
United States locations
- U.S. sites
- 24
- U.S. states
- 16
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's of Alabama/University of Alabama in Birmingham(UAB) | Birmingham | Alabama | 35233 | Recruiting |
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | Recruiting |
| City of Hope | Duarte | California | 91010 | Recruiting |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | Recruiting |
| UCLA Mattel Children's Hospital | Los Angeles | California | 90095 | Recruiting |
| UCSF Benioff Children's Hospital Oakland | Oakland | California | 94609 | Recruiting |
| UCSF | San Francisco | California | 94123 | Recruiting |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | Recruiting |
| Yale University School of Medicine | New Haven | Connecticut | 06520 | Recruiting |
| Alfred I. duPont Hospital for Children - Nemours Deleware | Wilmington | Delaware | 19803 | Recruiting |
| University of Florida | Gainesville | Florida | 32610 | Recruiting |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | Recruiting |
| Johns Hopkins All Children's Hospital | St. Petersburg | Florida | 33701 | Recruiting |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30322 | Recruiting |
| Riley Hospital for Children - Indiana University | Indianapolis | Indiana | 46202 | Recruiting |
| Floating Hospital for Children at Tufts Medical Center | Boston | Massachusetts | 02111 | Recruiting |
| Dana Faber Cancer Institute/ Boston Children's Hospital | Boston | Massachusetts | 02215 | Recruiting |
| Helen DeVos Children's Hospital at Spectrum Health | Grand Rapids | Michigan | 49503 | Recruiting |
| Children's Mercy Hospital | Kansas City | Missouri | 64108 | Recruiting |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | Recruiting |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | Recruiting |
| Atrium Health - Levine Cancer Center | Charlotte | North Carolina | 28203 | Recruiting |
| The University of Texas M. D. Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| Methodist Healthcare System | San Antonio | Texas | 78229 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03509961, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2025 · Synced May 16, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03509961 live on ClinicalTrials.gov.